Measurement of Total Circulating Blood Volume Following Subarachnoid Haemorrhage: Methodological Aspects

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1987 Sep 1

PMID 3668563

Citations 2

Authors

R J Nelson

J Roberts

D M Ackery

J D Pickard

Affiliations

Soon will be listed here.

Abstract

The total circulating blood volume (TCBV) and total body/venous haematocrit ratio (Htb/Hv) was determined by simultaneous measurement of the red cell volume (RCV) and the plasma volume (PV) in 10 subarachnoid haemorrhage (SAH) patients, 10 supine bedresting control patients and 20 ambulant out-patients. The mean Htb/Hv of the SAH patients, 0.866, was found to be significantly lower than that of the supine controls, 0.908, and the ambulant patients, 0.909, (p less than 0.01). Using the ratio 0.866 the total circulating blood volume of the SAH patients was calculated from either their RCV or their PV and compared with their measured TCBV. Expressed as a percentage of measured TCBV the mean errors of these single volume determinations were 2.84% and 1.76% respectively. The significance of these changes in the Htb/Hv ratio of SAH patients is discussed in relation to the circulatory disturbances they suffer.

Citing Articles

Timing of surgery for supratentorial aneurysmal subarachnoid haemorrhage: report of a prospective study.

Ross N, Hutchinson P, Seeley H, Kirkpatrick P J Neurol Neurosurg Psychiatry. 2002; 72(4):480-4.

PMID: 11909907 PMC: 1737846. DOI: 10.1136/jnnp.72.4.480.

An audit of aneurysmal subarachnoid haemorrhage: earlier resuscitation and surgery reduces inpatient stay and deaths from rebleeding.

Whitfield P, Moss H, OHare D, Smielewski P, Pickard J, Kirkpatrick P J Neurol Neurosurg Psychiatry. 1996; 60(3):301-6.

PMID: 8609508 PMC: 1073854. DOI: 10.1136/jnnp.60.3.301.

References

Mollison P, VEALL N, CUTBUSH M . Red cell and plasma volume in newborn infants. Arch Dis Child. 1950; 25(123):242-53. PMC: 1988304. DOI: 10.1136/adc.25.123.242. View

Davies J . A critical evaluation of red cell and plasma volume techniques in patients with burns. J Clin Pathol. 1960; 13:105-11. PMC: 480017. DOI: 10.1136/jcp.13.2.105. View

Gray S, Frank H . The simultaneous determination of red cell mass and plasma volume in man with radioactive sodium chromate and chromic chloride. J Clin Invest. 1953; 32(10):1000-4. PMC: 438433. DOI: 10.1172/JCI102810. View

Maroon J, Nelson P . Hypovolemia in patients with subarachnoid hemorrhage: therapeutic implications. Neurosurgery. 1979; 4(3):223-6. DOI: 10.1227/00006123-197903000-00005. View

Mason D, Bartter F . Autonomic regulation of blood volume. Anesthesiology. 1968; 29(4):681-92. DOI: 10.1097/00000542-196807000-00010. View

POLOSA C, HAMILTON W . Blood volume and intravascular hematocrit in different vascular beds. Am J Physiol. 1963; 204:903-9. DOI: 10.1152/ajplegacy.1963.204.5.903. View

Rothschild M, Bauman A, Yalow R, Berson S . Tissue distribution of I131 labeled human serum albumin following intravenous administration. J Clin Invest. 1955; 34(9):1354-8. PMC: 438706. DOI: 10.1172/JCI103183. View

Haraldsson B . Effects of noradrenaline on the transcapillary passage of albumin, fluid and CrEDTA in the perfused rat hindlimb. Acta Physiol Scand. 1985; 125(4):561-71. DOI: 10.1111/j.1748-1716.1985.tb07758.x. View

Benedict C, Loach A . Sympathetic nervous system activity in patients with subarachnoid hemorrhage. Stroke. 1978; 9(3):237-44. DOI: 10.1161/01.str.9.3.237. View

10.

EBERT R, Stead E . DEMONSTRATION THAT THE CELL PLASMA RATIO OF BLOOD CONTAINED IN MINUTE VESSELS IS LOWER THAN THAT OF VENOUS BLOOD. J Clin Invest. 1941; 20(3):317-21. PMC: 435062. DOI: 10.1172/JCI101225. View

11.

Rosing N . The normal metabolism of 131-I-labelled albumin in man. Clin Sci. 1967; 33(3):593-602. View

12.

GIBSON J, Seligman A, PEACOCK W, AUB J, Fine J, Evans R . THE DISTRIBUTION OF RED CELLS AND PLASMA IN LARGE AND MINUTE VESSELS OF THE NORMAL DOG, DETERMINED BY RADIOACTIVE ISOTOPES OF IRON AND IODINE. J Clin Invest. 1946; 25(6):848-57. PMC: 435630. DOI: 10.1172/JCI101772. View

13.

Solomon R, Post K, McMurtry 3rd J . Depression of circulating blood volume in patients after subarachnoid hemorrhage: implications for the management of symptomatic vasospasm. Neurosurgery. 1984; 15(3):354-61. DOI: 10.1227/00006123-198409000-00010. View

14.

CHAPLIN Jr H, Mollison P, Vetter H . The body/venous hematocrit ratio: its constancy over a wide hematocrit range. J Clin Invest. 1953; 32(12):1309-16. PMC: 438476. DOI: 10.1172/JCI102859. View

15.

VAN BEAUMONT W, Greenleaf J, Juhos L . Disproportional changes in hematocrit, plasma volume, and proteins during exercise and bed rest. J Appl Physiol. 1972; 33(1):55-61. DOI: 10.1152/jappl.1972.33.1.55. View

16.

Teasdale G, Jennett B . Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974; 2(7872):81-4. DOI: 10.1016/s0140-6736(74)91639-0. View

17.

Loria A, SANCHEZ-MEDAL L, KAUFFER N, QUINTANAR E . Relationship between body hematocrit and venous hematocrit in normal, splenomegalic, and anemic states. J Lab Clin Med. 1962; 60:396-408. View

18.

Neil-Dwyer G, Cruickshank J, Stott A, Brice J . The urinary catecholamine and plasma cortisol levels in patients with subarachnoid haemorrhage. J Neurol Sci. 1974; 22(3):375-82. DOI: 10.1016/0022-510x(74)90008-2. View

19.

Kudo T, Suzuki S, Iwabuchi T . Importance of monitoring the circulating blood volume in patients with cerebral vasospasm after subarachnoid hemorrhage. Neurosurgery. 1981; 9(5):514-20. DOI: 10.1227/00006123-198111000-00004. View

20.

Pritz M, Giannotta S, Kindt G, McGillicuddy J, PRAGER R . Treatment of patients with neurological deficits associated with cerebral vasospasm by intravascular volume expansion. Neurosurgery. 1978; 3(3):364-8. DOI: 10.1227/00006123-197811000-00006. View