Detection and Quantification of Myocardial Scar and LVEF with High Efficiency Digital SPECT: The Expanding Value Proposition for Clinical Cardiology

Overview

Journal J Nucl Cardiol

Specialty Cardiology & Vascular Diseases

Date 2023 Jan 22

PMID 36682016

Authors

Jeffrey S Fitch

Ronald G Schwartz

Affiliations

Soon will be listed here.

References

Boden W, ORourke R, Teo K, Hartigan P, Maron D, Kostuk W . Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007; 356(15):1503-16. DOI: 10.1056/NEJMoa070829. View

Shaw L, Berman D, Maron D, Mancini G, Hayes S, Hartigan P . Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. Circulation. 2008; 117(10):1283-91. DOI: 10.1161/CIRCULATIONAHA.107.743963. View

Taqueti V, Hachamovitch R, Murthy V, Naya M, Foster C, Hainer J . Global coronary flow reserve is associated with adverse cardiovascular events independently of luminal angiographic severity and modifies the effect of early revascularization. Circulation. 2014; 131(1):19-27. PMC: 4286486. DOI: 10.1161/CIRCULATIONAHA.114.011939. View

Gupta A, Taqueti V, van de Hoef T, Bajaj N, Bravo P, Murthy V . Integrated Noninvasive Physiological Assessment of Coronary Circulatory Function and Impact on Cardiovascular Mortality in Patients With Stable Coronary Artery Disease. Circulation. 2017; 136(24):2325-2336. PMC: 5726898. DOI: 10.1161/CIRCULATIONAHA.117.029992. View

Patel K, Spertus J, Chan P, Sperry B, Thompson R, Al Badarin F . Extent of Myocardial Ischemia on Positron Emission Tomography and Survival Benefit With Early Revascularization. J Am Coll Cardiol. 2019; 74(13):1645-1654. PMC: 6768093. DOI: 10.1016/j.jacc.2019.07.055. View

Gould K, Kitkungvan D, Johnson N, Nguyen T, Kirkeeide R, Bui L . Mortality Prediction by Quantitative PET Perfusion Expressed as Coronary Flow Capacity With and Without Revascularization. JACC Cardiovasc Imaging. 2020; 14(5):1020-1034. DOI: 10.1016/j.jcmg.2020.08.040. View

Ajufo E, Ayers C, Vigen R, Joshi P, Rohatgi A, de Lemos J . Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease. JAMA Cardiol. 2020; 6(2):179-187. PMC: 7593878. DOI: 10.1001/jamacardio.2020.4939. View

Krone R, Gregory J, Freedland K, Kleiger R, Wackers F, Bodenheimer M . Limited usefulness of exercise testing and thallium scintigraphy in evaluation of ambulatory patients several months after recovery from an acute coronary event: implications for management of stable coronary heart disease. Multicenter Myocardial.... J Am Coll Cardiol. 1994; 24(5):1274-81. DOI: 10.1016/0735-1097(94)90109-0. View

Kwong R, Chan A, Brown K, Chan C, Reynolds H, Tsang S . Impact of unrecognized myocardial scar detected by cardiac magnetic resonance imaging on event-free survival in patients presenting with signs or symptoms of coronary artery disease. Circulation. 2006; 113(23):2733-43. DOI: 10.1161/CIRCULATIONAHA.105.570648. View

10.

Kwong R, Sattar H, Wu H, Vorobiof G, Gandla V, Steel K . Incidence and prognostic implication of unrecognized myocardial scar characterized by cardiac magnetic resonance in diabetic patients without clinical evidence of myocardial infarction. Circulation. 2008; 118(10):1011-20. PMC: 2743310. DOI: 10.1161/CIRCULATIONAHA.107.727826. View

11.

Otaki Y, Betancur J, Sharir T, Hu L, Gransar H, Liang J . 5-Year Prognostic Value of Quantitative Versus Visual MPI in Subtle Perfusion Defects: Results From REFINE SPECT. JACC Cardiovasc Imaging. 2019; 13(3):774-785. PMC: 6899217. DOI: 10.1016/j.jcmg.2019.02.028. View

12.

Sharir T, Kang X, Germano G, Bax J, Shaw L, Gransar H . Prognostic value of poststress left ventricular volume and ejection fraction by gated myocardial perfusion SPECT in women and men: gender-related differences in normal limits and outcomes. J Nucl Cardiol. 2006; 13(4):495-506. DOI: 10.1016/j.nuclcard.2006.03.019. View

13.

Germano G, Kiat H, Kavanagh P, Moriel M, Mazzanti M, Su H . Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995; 36(11):2138-47. View

14.

Yamaguchi H, Toba M, Amano Y, Ishihara K, Mizuno K, Kumita S . Underestimation of the ejection fraction using the quantitative gated SPECT for patients with myocardial hypertrophy. Ann Nucl Med. 2013; 27(6):502-7. DOI: 10.1007/s12149-013-0713-9. View

15.

Hedeer F, Ostenfeld E, Heden B, Prinzen F, Arheden H, Carlsson M . To what extent are perfusion defects seen by myocardial perfusion SPECT in patients with left bundle branch block related to myocardial infarction, ECG characteristics, and myocardial wall motion?. J Nucl Cardiol. 2020; 28(6):2910-2922. PMC: 8709823. DOI: 10.1007/s12350-020-02180-7. View

16.

Nakazato R, Slomka P, Fish M, Schwartz R, Hayes S, Thomson L . Quantitative high-efficiency cadmium-zinc-telluride SPECT with dedicated parallel-hole collimation system in obese patients: results of a multi-center study. J Nucl Cardiol. 2014; 22(2):266-75. PMC: 4355061. DOI: 10.1007/s12350-014-9984-3. View

17.

Otaki Y, Manabe O, Miller R, Manrique A, Nganoa C, Roth N . Quantification of myocardial blood flow by CZT-SPECT with motion correction and comparison with O-water PET. J Nucl Cardiol. 2019; 28(4):1477-1486. PMC: 7042031. DOI: 10.1007/s12350-019-01854-1. View

18.

Lachant D, Light A, Mackin M, Schwartz R, White R . Heart Rate Expenditure Correlates with Right Ventricular Function. Ann Am Thorac Soc. 2019; 17(3):372-375. PMC: 7047316. DOI: 10.1513/AnnalsATS.201909-683RL. View

19.

Schwartz R, Jain D, Storozynsky E . Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively. J Nucl Cardiol. 2013; 20(3):443-64. DOI: 10.1007/s12350-013-9707-1. View

20.

Notohamiprodjo S, Nekolla S, Robu S, Villagran Asiares A, Kupatt C, Ibrahim T . Imaging of cardiac fibroblast activation in a patient after acute myocardial infarction using Ga-FAPI-04. J Nucl Cardiol. 2021; 29(5):2254-2261. PMC: 9553764. DOI: 10.1007/s12350-021-02603-z. View