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Spatial Optimization to Improve COVID-19 Vaccine Allocation

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Date 2023 Jan 21
PMID 36679909
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Abstract

Early distribution of COVID-19 vaccines was largely driven by population size and did not account for COVID-19 prevalence nor location characteristics. In this study, we applied an optimization framework to identify distribution strategies that would have lowered COVID-19 related morbidity and mortality. During the first half of 2021 in the state of Missouri, optimized vaccine allocation would have decreased case incidence by 8% with 5926 fewer COVID-19 cases, 106 fewer deaths, and 4.5 million dollars in healthcare cost saved. As COVID-19 variants continue to be identified, and the likelihood of future pandemics remains high, application of resource optimization should be a priority for policy makers.

References
1.
Lurie N, Saville M, Hatchett R, Halton J . Developing Covid-19 Vaccines at Pandemic Speed. N Engl J Med. 2020; 382(21):1969-1973. DOI: 10.1056/NEJMp2005630. View

2.
Buckner J, Chowell G, Springborn M . Dynamic prioritization of COVID-19 vaccines when social distancing is limited for essential workers. Proc Natl Acad Sci U S A. 2021; 118(16). PMC: 8072365. DOI: 10.1073/pnas.2025786118. View

3.
Klise K, Beyeler W, Finley P, Makvandi M . Analysis of mobility data to build contact networks for COVID-19. PLoS One. 2021; 16(4):e0249726. PMC: 8049304. DOI: 10.1371/journal.pone.0249726. View

4.
Boutros M, Moujaess E, Kourie H . Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea. Crit Rev Oncol Hematol. 2021; 167:103273. PMC: 7959683. DOI: 10.1016/j.critrevonc.2021.103273. View

5.
Matrajt L, Eaton J, Leung T, Dimitrov D, Schiffer J, Swan D . Optimizing vaccine allocation for COVID-19 vaccines shows the potential role of single-dose vaccination. Nat Commun. 2021; 12(1):3449. PMC: 8187351. DOI: 10.1038/s41467-021-23761-1. View