Design and Detection of Cyanide Raman Tag PH-Responsive SERS Probes

Overview

Journal Biosensors (Basel)

Specialty Biotechnology

Date 2023 Jan 21

PMID 36671856

Authors

Jingjing Shen

Guan Liu

Wen Zhang

Wenwen Shi

Yang Zhou

Zejie Yu

Qunbo Mei

Lei Zhang

Wei Huang

Affiliations

Soon will be listed here.

Abstract

As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. In this paper, a pH-responsive SERS probe based on the cyano Raman Tag was designed to realize pH sensing detection through the influence of the pH value of analytes on the displacement of the cyano Raman peak in the SERS probe. This cyano Raman tag exhibited not only excellent sensitivity in the liner range of pH 3.0-9.0 with a limit of detection (LOD) of pH 0.33, but also the anti-interference performance and stability (the relative standard deviation (RSD) was calculated to be 6.68%, = 5). These results indicated that this pH SERS probe with the Raman cyano tag can provide new research ideas for future biological detection, bioimaging, and environmental detection.

References

Liu R, Zhao J, Han G, Zhao T, Zhang R, Liu B . Click-Functionalized SERS Nanoprobes with Improved Labeling Efficiency and Capability for Cancer Cell Imaging. ACS Appl Mater Interfaces. 2017; 9(44):38222-38229. DOI: 10.1021/acsami.7b10409. View

Gutierrez-Sanz O, Forbrig E, Batista A, Pereira M, Salewski J, Mroginski M . Catalytic Activity and Proton Translocation of Reconstituted Respiratory Complex I Monitored by Surface-Enhanced Infrared Absorption Spectroscopy. Langmuir. 2018; 34(20):5703-5711. DOI: 10.1021/acs.langmuir.7b04057. View

Sun J, Zhang Z, Liu C, Dai X, Zhou W, Jiang K . Continuous in situ portable SERS analysis of pollutants in water and air by a highly sensitive gold nanoparticle-decorated PVDF substrate. Anal Bioanal Chem. 2021; 413(21):5469-5482. DOI: 10.1007/s00216-021-03531-0. View

Hao N, Lu J, Zhou Z, Hua R, Wang K . A pH-Resolved Colorimetric Biosensor for Simultaneous Multiple Target Detection. ACS Sens. 2018; 3(10):2159-2165. DOI: 10.1021/acssensors.8b00717. View

Chen H, Luo C, Zhang S . Intracellular imaging and concurrent pH sensing of cancer-derived exosomes using surface-enhanced Raman scattering. Anal Bioanal Chem. 2021; 413(15):4091-4101. DOI: 10.1007/s00216-021-03365-w. View

Shen Y, Liang L, Zhang S, Huang D, Zhang J, Xu S . Organelle-targeting surface-enhanced Raman scattering (SERS) nanosensors for subcellular pH sensing. Nanoscale. 2017; 10(4):1622-1630. DOI: 10.1039/c7nr08636a. View

Xie M, Li F, Gu P, Wang F, Qu Z, Li J . Gold nanoflower-based surface-enhanced Raman probes for pH mapping of tumor cell microenviroment. Cell Prolif. 2019; 52(4):e12618. PMC: 6669020. DOI: 10.1111/cpr.12618. View

Chen Z, Lu S, Zhang Z, Huang X, Zhao H, Wei J . Green photoreduction synthesis of dispersible gold nanoparticles and their direct in situ assembling in multidimensional substrates for SERS detection. Mikrochim Acta. 2022; 189(8):275. DOI: 10.1007/s00604-022-05379-2. View

Bastus N, Comenge J, Puntes V . Kinetically controlled seeded growth synthesis of citrate-stabilized gold nanoparticles of up to 200 nm: size focusing versus Ostwald ripening. Langmuir. 2011; 27(17):11098-105. DOI: 10.1021/la201938u. View

10.

Damaghi M, Wojtkowiak J, Gillies R . pH sensing and regulation in cancer. Front Physiol. 2014; 4:370. PMC: 3865727. DOI: 10.3389/fphys.2013.00370. View

11.

Lu Q, Wang Y, Chen H, Wang Q, Yang X, Zou L . A rise in saliva and urine pH in children with -related epilepsy: An exploratory prospective controlled study. Front Neurol. 2022; 13:982050. PMC: 9552845. DOI: 10.3389/fneur.2022.982050. View

12.

Zhou X, Hu Z, Yang D, Xie S, Jiang Z, Niessner R . Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques. Adv Sci (Weinh). 2020; 7(23):2001739. PMC: 7710000. DOI: 10.1002/advs.202001739. View

13.

Chaudhari R, Joshi A, Srivastava R . pH and Urea Estimation in Urine Samples using Single Fluorophore and Ratiometric Fluorescent Biosensors. Sci Rep. 2017; 7(1):5840. PMC: 5517509. DOI: 10.1038/s41598-017-06060-y. View

14.

Guo J, Rubfiaro A, Lai Y, Moscoso J, Chen F, Liu Y . Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette. Analyst. 2020; 145(14):4852-4859. PMC: 7425357. DOI: 10.1039/d0an00838a. View

15.

Yang S, Liu W, Li G, Bu R, Li P, Gao E . A pH-Sensing Fluorescent Metal-Organic Framework: pH-Triggered Fluorescence Transition and Detection of Mycotoxin. Inorg Chem. 2020; 59(20):15421-15429. DOI: 10.1021/acs.inorgchem.0c02419. View

16.

Shaibani P, Etayash H, Naicker S, Kaur K, Thundat T . Metabolic Study of Cancer Cells Using a pH Sensitive Hydrogel Nanofiber Light Addressable Potentiometric Sensor. ACS Sens. 2017; 2(1):151-156. DOI: 10.1021/acssensors.6b00632. View

17.

Zheng Y, Chen Z, Zheng C, Lee Y, Hou X, Wu L . Derivatization reaction-based surface-enhanced Raman scattering (SERS) for detection of trace acetone. Talanta. 2016; 155:87-93. DOI: 10.1016/j.talanta.2016.04.024. View

18.

Zhang D, Fang J, Li T . Sensitive and uniform detection using Surface-Enhanced Raman Scattering: Influence of colloidal-droplets evaporation based on Au-Ag alloy nanourchins. J Colloid Interface Sci. 2017; 514:217-226. DOI: 10.1016/j.jcis.2017.12.017. View

19.

Li H, Men D, Sun Y, Liu D, Li X, Li L . Surface enhanced Raman scattering properties of dynamically tunable nanogaps between Au nanoparticles self-assembled on hydrogel microspheres controlled by pH. J Colloid Interface Sci. 2017; 505:467-475. DOI: 10.1016/j.jcis.2017.06.034. View

20.

Sun J, Mao Y, Guo Z, Zhang Y, Gu N . Time-varied magnetic-field induced monolayer formation and re-aggregation of Au nanoparticles during solvent evaporation. J Nanosci Nanotechnol. 2009; 9(2):1156-9. DOI: 10.1166/jnn.2009.c109. View