» Articles » PMID: 36671010

Dietary Protein Levels Modulate the Antioxidant Capacity During Different Growth Stages in Huanjiang Mini-Pigs

Overview
Date 2023 Jan 21
PMID 36671010
Authors
Affiliations
Soon will be listed here.
Abstract

Adequate crude protein (CP) levels in diets play potential roles in swine production. This study determined the impacts of different CP levels on the antioxidant capacity of pigs during different body weight (BW) stages. Three hundred and sixty Huanjiang mini-pigs were allocated to one of three independent experiments, including a 5−10 kg BW group, where CP levels included 14%, 16%, 18%, 20%, and 22%; a 10−20 kg BW group, where CP levels included 12%, 14%, 16%, 18%, and 20%; and a 20−30 kg BW group, where CP levels included 10%, 12%, 14%, 16%, and 18%. These independent experiments were conducted for 28, 28, and 26 days, respectively. Results showed that the 20% CP level increased (p < 0.05) the plasma CAT and GSH-Px activities and the GSH concentration of pigs than in the pigs supplemented with the 14−18% CP levels, and the 20% CP level up-regulated (p < 0.05) the ileal oxidative stress-related gene expression levels of pigs than in the pigs supplemented with the 14% CP level at the 5−10 kg BW. In addition, diets supplemented with 18% CP level increased (p < 0.05) the ileal GSH concentration of pigs than in the pigs supplemented with the 14% and 20% CP levels, and the 16−18% CP levels increased (p < 0.05) the jejunal SOD activity of pigs than in the pigs supplemented with the 14% CP level. At 10−20 kg BW, the 16% CP level presented the strongest jejunal and ileal antioxidant capacity, the 18% CP level had the lowest plasma concentrations of MDA and highest GSH, and the 14−16% CP levels increased the plasma CAT and SOD activities (p < 0.05). Moreover, the 16−20% CP levels up-regulated (p < 0.05) the oxidative stress-related gene expression levels. At 20−30 kg BW, diets supplemented with the 16% CP level increased the plasma CAT activity of pigs than in the pigs supplemented with the 12−14% CP levels, and the 14−16% CP levels decreased the MDA concentration compared with the 10% CP levels (p < 0.05). In conclusion, these findings indicate adequate CP levels of 20%, 16%, and 14% for Huanjiang mini-pigs at the 5−10, 10−20, and 20−30 kg BW stages, respectively.

Citing Articles

Responses in weanling pigs fed low protein diets supplemented with dietary nucleotides.

Lawal A, Ogunribido T, Fu Y, Adeola O, Ajuwon K Transl Anim Sci. 2024; 8:txae142.

PMID: 39444714 PMC: 11497618. DOI: 10.1093/tas/txae142.


Crude protein content in diets associated with intestinal microbiome and metabolome alteration in Huanjiang mini-pigs during different growth stages.

Liu Y, Azad M, Zhao X, Kong X Front Microbiol. 2024; 15:1398919.

PMID: 38690359 PMC: 11058986. DOI: 10.3389/fmicb.2024.1398919.


Antioxidant Capacity, Inflammatory Response, Carcass Characteristics and Meat Quality of Hu Sheep in Response to Dietary Soluble Protein Levels with Decreased Crude Protein Content.

Zhang X, Zhang Z, Sun Y, Liu Y, Zhong X, Zhu J Antioxidants (Basel). 2023; 12(12).

PMID: 38136218 PMC: 10741046. DOI: 10.3390/antiox12122098.

References
1.
Mohamed L, El-Hindawy M, Alagawany M, Salah A, El-Sayed S . Effect of low- or high-CP diet with cold-pressed oil supplementation on growth, immunity and antioxidant indices of growing quail. J Anim Physiol Anim Nutr (Berl). 2019; 103(5):1380-1387. DOI: 10.1111/jpn.13121. View

2.
dAlessandro E, Arfuso F, Floridia V, Tardiolo G, Fazio F, Giannetto C . Different genotype and a liquid whey-supplemented diet influence the resilience of pigs through immune-modulation and anti-inflammatory response. Front Vet Sci. 2022; 9:1046101. PMC: 9683634. DOI: 10.3389/fvets.2022.1046101. View

3.
Zhu L, Zhao K, Chen X, Xu J . Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs. J Anim Sci. 2012; 90(8):2581-9. DOI: 10.2527/jas.2012-4444. View

4.
Gonzalez-Manan D, DEspessailles A, Dossi C, San Martin M, Mancilla R, Tapia G . Rosa Mosqueta Oil Prevents Oxidative Stress and Inflammation through the Upregulation of PPAR-α and NRF2 in C57BL/6J Mice Fed a High-Fat Diet. J Nutr. 2017; 147(4):579-588. DOI: 10.3945/jn.116.243261. View

5.
Wang K, Kong X, Azad M, Zhu Q, Xiong L, Zheng Y . Maternal Probiotic or Synbiotic Supplementation Modulates Jejunal and Colonic Antioxidant Capacity, Mitochondrial Function, and Microbial Abundance in Bama Mini-piglets. Oxid Med Cell Longev. 2021; 2021:6618874. PMC: 8116152. DOI: 10.1155/2021/6618874. View