Life Mimics Art
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Overview
Authors
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Affiliations
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References
1.
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. Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders. Chem Soc Rev. 2022; 51(15):6234-6250.
DOI: 10.1039/d2cs00116k.
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2.
Choi T, Lee S, Kim Y, Bae J, Lee K, Jo Y
. Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel. J Neurosci. 2018; 38(14):3571-3583.
PMC: 6596048.
DOI: 10.1523/JNEUROSCI.2081-17.2018.
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3.
Jan M, Sperling A, Ebert B
. Cancer therapies based on targeted protein degradation - lessons learned with lenalidomide. Nat Rev Clin Oncol. 2021; 18(7):401-417.
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Kim J, Scialli A
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Ichikawa S, Flaxman H, Xu W, Vallavoju N, Lloyd H, Wang B
. The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron. Nature. 2022; 610(7933):775-782.
PMC: 10316063.
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