» Articles » PMID: 36644589

Isotopic Production Cross Sections in Proton-16O and Proton-12C Interactions for Energies from 10 MeV/u to 100 GeV/u

Overview
Date 2023 Jan 16
PMID 36644589
Authors
Affiliations
Soon will be listed here.
Abstract

Proton interactions with O or C nuclei are frequent nuclear interaction leading to secondary radiation in tissues for space radiation and cancer therapy with protons or ion beams. The fragmentation of these ions by protons produces a large number of heavy ion (A>4) target or projectile fragments often with high ionization density. Here we develop an analytical model of energy dependent proton-O and proton-C cross sections for isotopic nuclei production. Using experimental data and a 2 order optical model an accurate formula for the absorption cross section from <10 MeV/u to >10 GeV/u is obtained. The energy dependence of the elemental and isotopic cross sections is modeled as multiplicities scaled to absorption cross section with average isotopic fractions estimated from experimental data. We show that this approach results in accurate analytic formulae for isotopic fragmentation cross sections over the full energy range in hadron therapy and space radiation protection studies.

References
1.
Masuda T, Kataoka J, Arimoto M, Takabe M, Nishio T, Matsushita K . Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy. Sci Rep. 2018; 8(1):2570. PMC: 5803244. DOI: 10.1038/s41598-018-20906-z. View

2.
Schulz-Ertner D, Tsujii H . Particle radiation therapy using proton and heavier ion beams. J Clin Oncol. 2007; 25(8):953-64. DOI: 10.1200/JCO.2006.09.7816. View

3.
Abousaida B, Seneviratne D, Hoppe B, Ko S, Asaithamby A, Cucinotta F . Carbon Ion Radiotherapy in the Management of Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2021; 8:1169-1179. PMC: 8478421. DOI: 10.2147/JHC.S292516. View

4.
Webber , Kish , Schrier . Total charge and mass changing cross sections of relativistic nuclei in hydrogen, helium, and carbon targets. Phys Rev C Nucl Phys. 1990; 41(2):520-532. DOI: 10.1103/physrevc.41.520. View

5.
Yan C, Saganti P, Cucinotta F . Study of Total, Absorption, and He and H Production Cross Sections in He-proton Collisions. Nucl Instrum Methods Phys Res B. 2021; 502:136-141. PMC: 8654085. DOI: 10.1016/j.nimb.2021.06.013. View