Zinc Acetate Dihydrate Tablet-Associated Gastritis Occurring in a Post-Hematopoietic Stem Cell Transplant Recipient

Overview

Journal Case Rep Gastrointest Med

Publisher Wiley

Specialty Gastroenterology

Date 2023 Jan 10

PMID 36624891

Authors

Masaya Iwamuro

Takehiro Tanaka

Akifumi Matsumura

Seiji Kawano

Yoshiro Kawahara

Hiroyuki Okada

Affiliations

Soon will be listed here.

Abstract

A 65-year-old Japanese woman underwent umbilical cord blood transplantation for acute myeloid leukemia. Zinc acetate dihydrate tablets were administered for hypozincemia after transplantation, and vomiting and appetite loss occurred soon thereafter. Esophagogastroduodenoscopy revealed mucosal redness, erosion, white coat adhesion, and ulcers. Although graft-versus-host disease, intestinal transplant-associated microangiopathy, and cytomegalovirus infection were considered as possible causes, we diagnosed the patient with zinc acetate dihydrate tablet-associated gastric mucosal alterations based on the endoscopic features. This case reinforces the notion that medication-associated gastric lesions should be suspected in patients taking zinc acetate dihydrate tablets.

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