Melanin Synthesis Inhibition Activity of Compounds Isolated from Bamboo Shoot Skin ()

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2023 Jan 8

PMID 36615219

Authors

Ahmed Ashour

Ahmed Elbermawi

Yhiya Amen

Ahmed E Allam

Hiromi Ikeda

Maki Nagata

Kenta Kumagae

Tomoyo Azuma

Aya Taguchi

Takuya Takemoto

Masako Matsumoto

Kuniyoshi Shimizu

Affiliations

Soon will be listed here.

Abstract

This study targets the evaluation of melanin synthesis inhibition activity of the bamboo shoot skin as agro-waste. The total methanolic extract of bamboo peel extract was evaluated for its skin protective effects via measuring its melanin inhibitory activity and its suppression activity on the expression of tyrosinase mRNA levels. Results showed that bamboo peel extract has a good ability for the inhibition of melanin synthesis so further studies were performed for the isolation of its constituents. Twelve compounds have been isolated from the shoot skin of . Their structures were elucidated based on extensive spectroscopic methods. The melanin inhibition potential of the isolates was tested with their collagen-production-promoting activity for the determination of active principles. Results showed that Betulinic acid, tachioside, and 1,2-dilinolenin significantly suppressed melanin production per cell compared to control. Triacontanol, tricin, and (+)-lyoniresinol 9'--glucoside also tended to decrease melanin production per cell. These findings indicated that the skin of bamboo shoots, a significant agricultural waste, is a useful natural source for further research on its potential for aging problems such hyperpigmentation and cognitive function impairment.

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