Post-Cardiac Arrest: Mechanisms, Management, and Future Perspectives

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Jan 8

PMID 36615059

Authors

Taline Lazzarin

Carolina Rodrigues Tonon

Danilo Martins

Edson Luiz Favero Jr

Thiago Dias Baumgratz

Filipe Welson Leal Pereira

Victor Rocha Pinheiro

Raquel Simoes Ballarin

Diego Aparecido Rios Queiroz

Paula Schmidt Azevedo

Bertha Furlan Polegato

Marina Politi Okoshi

Leonardo Zornoff

Sergio Alberto Rupp de Paiva

Marcos Ferreira Minicucci

Affiliations

Soon will be listed here.

Abstract

Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to 22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest syndrome, which is characterized by the ischemia-reperfusion injury that affects the role body. Understanding physiopathology is mandatory to discover new treatment strategies and obtain better results. Besides improvements in cardiopulmonary resuscitation maneuvers, the great increase in survival rates observed in recent decades is due to new approaches to post-cardiac arrest care. In this review, we will discuss physiopathology, etiologies, and post-resuscitation care, emphasizing targeted temperature management, early coronary angiography, and rehabilitation.

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