The Therapeutic Effects of Low-intensity Pulsed Ultrasound in Musculoskeletal Soft Tissue Injuries: Focusing on the Molecular Mechanism

Overview

Journal Front Bioeng Biotechnol

Date 2023 Jan 2

PMID 36588943

Authors

Haocheng Qin

Liang Du

Zhiwen Luo

Zhong He

Qing Wang

Shiyi Chen

Yu-Lian Zhu

Affiliations

Soon will be listed here.

Abstract

Musculoskeletal soft tissue injuries are very common and usually occur during both sporting and everyday activities. The intervention of adjuvant therapies to promote tissue regeneration is of great importance to improving people's quality of life and extending their productive lives. Though many studies have focused on the positive results and effectiveness of the LIPUS on soft tissue, the molecular mechanisms standing behind LIPUS effects are much less explored and reported, especially the intracellular signaling pathways. We incorporated all research on LIPUS in soft tissue diseases since 2005 and summarized studies that uncovered the intracellular molecular mechanism. This review will also provide the latest evidence-based research progress in this field and suggest research directions for future experiments.

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