How Lymphatic Endothelial Cells Destabilize Regulatory T Cells

Overview

Journal Arterioscler Thromb Vasc Biol

Date 2022 Dec 29

PMID 36579643

Authors

Qingkang Lyu

Klaus Ley

Affiliations

Soon will be listed here.

References

Ali A, Makings J, Ley K . Regulatory T Cell Stability and Plasticity in Atherosclerosis. Cells. 2020; 9(12). PMC: 7764358. DOI: 10.3390/cells9122665. View

Miyazaki T, Taketomi Y, Higashi T, Ohtaki H, Takaki T, Ohnishi K . Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking. Arterioscler Thromb Vasc Biol. 2022; 43(2):e66-e82. DOI: 10.1161/ATVBAHA.122.317781. View

Cui W, Zhou J, Dehne N, Brune B . Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages. Cell Biosci. 2015; 5:36. PMC: 4491253. DOI: 10.1186/s13578-015-0026-x. View

Glading A, Lauffenburger D, Wells A . Cutting to the chase: calpain proteases in cell motility. Trends Cell Biol. 2002; 12(1):46-54. DOI: 10.1016/s0962-8924(01)02179-1. View

Li F, Cai P, Song L, Zhou L, Zhang Q, Rao S . Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis. Biochim Biophys Acta. 2015; 1852(9):1796-804. DOI: 10.1016/j.bbadis.2015.06.008. View

Bhat O, Uday Kumar P, Harishankar N, Ravichandaran L, Bhatia A, Dhawan V . Interleukin-18-induced cell adhesion molecule expression is associated with feedback regulation by PPAR-γ and NF-κB in Apo E-/- mice. Mol Cell Biochem. 2017; 428(1-2):119-128. DOI: 10.1007/s11010-016-2922-8. View

Murai M, Krause P, Cheroutre H, Kronenberg M . Regulatory T-cell stability and plasticity in mucosal and systemic immune systems. Mucosal Immunol. 2010; 3(5):443-9. PMC: 2924438. DOI: 10.1038/mi.2010.27. View

Li J, McArdle S, Gholami A, Kimura T, Wolf D, Gerhardt T . CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis. Circ Res. 2016; 118(10):1540-52. PMC: 4867125. DOI: 10.1161/CIRCRESAHA.116.308648. View

Carragher N, Frame M . Calpain: a role in cell transformation and migration. Int J Biochem Cell Biol. 2002; 34(12):1539-43. DOI: 10.1016/s1357-2725(02)00069-9. View

10.

Gaddis D, Padgett L, Wu R, McSkimming C, Romines V, Taylor A . Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. Nat Commun. 2018; 9(1):1095. PMC: 5854619. DOI: 10.1038/s41467-018-03493-5. View

11.

Prangsaengtong O, Senda K, Doki Y, Park J, Jo M, Sakurai H . Calpain 1 and -2 play opposite roles in cord formation of lymphatic endothelial cells via eNOS regulation. Hum Cell. 2012; 25(2):36-44. DOI: 10.1007/s13577-012-0042-7. View

12.

Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M . Regulatory CD4 T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B. Circulation. 2018; 138(11):1130-1143. PMC: 6160361. DOI: 10.1161/CIRCULATIONAHA.117.031420. View

13.

Mallat Z, Gojova A, Marchiol-Fournigault C, Esposito B, Kamate C, Merval R . Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice. Circ Res. 2001; 89(10):930-4. DOI: 10.1161/hh2201.099415. View

14.

Miyazaki T, Taketomi Y, Takimoto M, Lei X, Arita S, Kim-Kaneyama J . m-Calpain induction in vascular endothelial cells on human and mouse atheromas and its roles in VE-cadherin disorganization and atherosclerosis. Circulation. 2011; 124(23):2522-32. DOI: 10.1161/CIRCULATIONAHA.111.021675. View