Editorial: Adenylyl Cyclase Isoforms As Potential Drug Targets

Santos R, Ursu O, Gaulton A, Bento A, Donadi R, Bologa C . A comprehensive map of molecular drug targets. Nat Rev Drug Discov. 2016; 16(1):19-34. PMC: 6314433. DOI: 10.1038/nrd.2016.230. View

Brust T, Alongkronrusmee D, Soto-Velasquez M, Baldwin T, Ye Z, Dai M . Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties. Sci Signal. 2017; 10(467). PMC: 5734633. DOI: 10.1126/scisignal.aah5381. View

Ostrom K, LaVigne J, Brust T, Seifert R, Dessauer C, Watts V . Physiological roles of mammalian transmembrane adenylyl cyclase isoforms. Physiol Rev. 2021; 102(2):815-857. PMC: 8759965. DOI: 10.1152/physrev.00013.2021. View