Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia

Overview

Journal Rev J Autism Dev Disord

Date 2022 Dec 26

PMID 36568688

Authors

Emily J Levy

Jennifer Foss-Feig

Emily L Isenstein

Vinod Srihari

Alan Anticevic

Adam J Naples

James C McPartland

Affiliations

Soon will be listed here.

Abstract

Autism spectrum disorder (ASD) and schizophrenia spectrum disorders (SZ) are characterized by difficulty with social cognition and atypical reception of facial communication - a key area in the Research Domain Criteria framework. To identify areas of overlap and dissociation between ASD and SZ, we review studies of event-related potentials (ERP) to faces across ASD and SZ populations, focusing on ERPs implicated in social perception: P100, N170, N250, and P300. There were many inconsistent findings across studies; however, replication was strongest for delayed N170 latency in ASD and attenuated N170 amplitude in SZ. These results highlight the challenges of replicating research findings in heterogeneous clinical populations and the need for transdiagnostic research that continuously quantifies behavior and neural activity across neurodevelopmental disorders.

Citing Articles

Intervention Effect of Group Sensory Integration Training on Social Responsiveness and N170 Event-Related Potential of Children with Autism.

Shu D, Zhang G, Xue C, Lai Q, He Y, Feng Y Behav Sci (Basel). 2024; 14(3).

PMID: 38540505 PMC: 10967769. DOI: 10.3390/bs14030202.

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