The Role of Heme Oxygenase-1 As an Immunomodulator in Kidney Disease

Overview

Journal Antioxidants (Basel)

Date 2022 Dec 23

PMID 36552662

Authors

Virginia Athanassiadou

Stella Plavoukou

Eirini Grapsa

Maria G Detsika

Affiliations

Soon will be listed here.

Abstract

The protein heme oxygenase (HO)-1 has been implicated in the regulations of multiple immunological processes. It is well known that kidney injury is affected by immune mechanisms and that various kidney-disease forms may be a result of autoimmune disease. The current study describes in detail the role of HO-1 in kidney disease and provides the most recent observations of the effect of HO-1 on immune pathways and responses both in animal models of immune-mediated disease forms and in patient studies.

Citing Articles

The roles of heme oxygenase-1 in renal disease.

Zhai H, Ni L, Wu X Front Nephrol. 2023; 3:1156346.

PMID: 37675385 PMC: 10479750. DOI: 10.3389/fneph.2023.1156346.

Lianos E, Detsika M Antioxidants (Basel). 2023; 12(7).

PMID: 37507862 PMC: 10376276. DOI: 10.3390/antiox12071322.

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