Combining Superselective Catheterization and Electrochemotherapy: A New Technological Approach to the Treatment of High-flow Head and Neck Vascular Malformations

Overview

Journal Front Oncol

Specialty Oncology

Date 2022 Dec 16

PMID 36523962

Authors

Aljosa Krt

Maja Cemazar

Dimitrij Lovric

Gregor Sersa

Crt Jamsek

Ales Groselj

Affiliations

Soon will be listed here.

Abstract

Introduction: The study aims to demonstrate a combination of superselective catheterization and electrochemotherapy as a feasible and effective new technological approach in treating high-flow vascular malformations of the head and neck region.

Patients And Methods: In the patient with high-flow arteriovenous malformation of the lower lip, superselective catheterization was performed under general anesthesia. The microcatheter was used to administer 750 IU BLM intra-arterially into the feeding vessel. The whole malformation surface was then covered with 15 applications of electric pulses using the plate electrode.

Results: Excellent response, without functional or aesthetic deficits, was obtained in 10 weeks. During this period, debridement and necrectomy were performed regularly on follow-up visits. The pain was managed with oral paracetamol and sodium metamizole.

Conclusion: Combining electrochemotherapy using bleomycin with superselective catheterization and arteriography is a feasible treatment option for high-flow vascular malformations in the head and neck region and could play a significant role in managing these challenging lesions.

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