» Articles » PMID: 36521446

From Dyspnea to Skin Grafting: The Difficulties of Managing a Patient with Extreme Obesity

Overview
Journal Obes Facts
Publisher Karger
Specialty Endocrinology
Date 2022 Dec 15
PMID 36521446
Authors
Affiliations
Soon will be listed here.
Abstract

While the prevalence of severe obesity is increasing worldwide, caregivers are often challenged with the management of patients with extreme weight. A 30-year-old woman (weight 245 kg, body mass index 85 kg/m2) presented with dyspnea, for which investigations led to suspect pulmonary embolism. The patient's weight made it impossible to perform adapted imaging; thus, an empirical anticoagulant treatment was initiated. A hematoma of the thigh occurred as a consequence of a transient antivitamin K overdose, leading to a 15-cm necrotic wound worsened by a state of malnutrition. Multidisciplinary and comprehensive care was performed including wound trimming, antibiotics, skin grafting, treatment of malnutrition, and psychological support, but with marked difficulties due to the lack of adapted medical equipment and facilities as well as appropriate medical guidelines. Overall, 7 months of hospitalization including 4 months of physiotherapy and rehabilitation were needed before the patient could return home. This case highlights how difficult managing patients with extreme obesity can be and points to the importance for healthcare systems to adapt to the specific needs of these patients and to design specific guidelines for treatment dosage and malnutrition prevention and treatment in this setting.

Citing Articles

Semaglutide Treatment in a Patient with Extreme Obesity and Massive Lymphedema: A Case Report.

Nguyen J, Barbet-Massin M, Pupier E, Larroumet A, Bosc L, Michelet M Obes Facts. 2024; 17(6):641-645.

PMID: 39250902 PMC: 11661835. DOI: 10.1159/000540241.

References
1.
Donini L, Busetto L, Bischoff S, Cederholm T, Ballesteros-Pomar M, Batsis J . Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement. Clin Nutr. 2022; 41(4):990-1000. DOI: 10.1016/j.clnu.2021.11.014. View

2.
Schwartz M, Chambliss H, Brownell K, Blair S, Billington C . Weight bias among health professionals specializing in obesity. Obes Res. 2003; 11(9):1033-9. DOI: 10.1038/oby.2003.142. View

3.
Meng L, Mui E, Holubar M, Deresinski S . Comprehensive Guidance for Antibiotic Dosing in Obese Adults. Pharmacotherapy. 2017; 37(11):1415-1431. DOI: 10.1002/phar.2023. View

4.
Martin K, Beyer-Westendorf J, Davidson B, Huisman M, Sandset P, Moll S . Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: Updated communication from the ISTH SSC Subcommittee on Control of Anticoagulation. J Thromb Haemost. 2021; 19(8):1874-1882. DOI: 10.1111/jth.15358. View

5.
Yarnoz-Esquiroz P, Olazaran L, Aguas-Ayesa M, Perdomo C, Garcia-Goni M, Silva C . 'Obesities': Position statement on a complex disease entity with multifaceted drivers. Eur J Clin Invest. 2022; 52(7):e13811. PMC: 9285368. DOI: 10.1111/eci.13811. View