» Articles » PMID: 36505544

Evaluation of Demographic and Rare Clinical Characteristics of Patients with Thoracic Carcinoid Tumor in Razi and Aria Hospitals of Rasht During 2006-2016

Abstract

Introduction: Carcinoid tumors are malignant neoplasms of neuroendocrine cells. This study tended to evaluate the demographic and rare clinical characteristics of patients with thoracic carcinoid tumor during 2006-2016 at Razi and Aria Hospitals in Rasht.

Materials And Methods: The present study was performed on records of 43 patients with lung carcinoid tumors referred to Razi and Aria Hospitals of Rasht during 2006-2016. Information on age, gender, rare clinical symptoms, smoking history, diagnosis tools, treatment, and outcome were analyzed.

Results: Of 43 patients treated with definitive diagnosis of carcinoid tumor pathology, 31 patients had typic carcinoid tumor and 12 patients with atypic carcinoma (mean age 43.14 ± 15.16 years). The most common clinical symptom was cough and hemoptysis. Two cases presented with cushing syndrome, The most common diagnostic method in this study was simultaneous use of both CT scans and bronchoscopy. In 95.3% of cases, the tumor was pulmonary and in 4.7% of cases, it was extrapulmonary. Right lower lobe was the most common site of tumors and most of the surgeries used were lobectomy.

Conclusion: This study showed that the most common clinical sign of thoracic carcinoid is cough and the tumor is pulmonary in 95.3% of cases. Right lower lobe was the most common site of tumors and most of the surgeries used were lobectomy. outcome was good.

References
1.
Patnaik A, Lieberman P, Hurvitz A, JOHNSON G . Canine hepatic carcinoids. Vet Pathol. 1981; 18(4):445-53. DOI: 10.1177/030098588101800404. View

2.
Jochmanova I, Abcede A, Guerrero R, Malong C, Wesley R, Huynh T . Clinical characteristics and outcomes of SDHB-related pheochromocytoma and paraganglioma in children and adolescents. J Cancer Res Clin Oncol. 2020; 146(4):1051-1063. PMC: 7388579. DOI: 10.1007/s00432-020-03138-5. View

3.
Durante C, Boukheris H, Dromain C, Duvillard P, Leboulleux S, Elias D . Prognostic factors influencing survival from metastatic (stage IV) gastroenteropancreatic well-differentiated endocrine carcinoma. Endocr Relat Cancer. 2009; 16(2):585-97. DOI: 10.1677/ERC-08-0301. View

4.
Hage R, Brutel de la Riviere A, Seldenrijk C, van den Bosch J . Update in pulmonary carcinoid tumors: a review article. Ann Surg Oncol. 2003; 10(6):697-704. DOI: 10.1245/aso.2003.09.019. View

5.
Gomez A, Zalacain R, Cabriada V, Lopez L, Cancelo L, Jaca C . [Bronchial carcinoid tumors. Analysis of 41 cases]. Rev Clin Esp. 2004; 204(4):202-5. DOI: 10.1157/13060271. View