Application Value and Safety of NIPPV Combined with Routine Clearance in the Treatment of Stroke-associated Pneumonia in Elderly Patients

Overview

Journal Am J Transl Res

Specialty General Medicine

Date 2022 Dec 12

PMID 36505335

Authors

Qiubo Zhang

Renfeng Zeng

XinHeng Tang

Affiliations

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Abstract

Objective: To investigate the application value and safety of NIPPV (noninvasive positive pressure ventilation) combined with routine clearance in elderly patients with stroke-associated pneumonia (SAP).

Methods: Altogether 88 elderly SAP patients treated in our hospital from January 2021 to January 2022 were retrospectively evaluated. Among them, 48 cases treated with NIPPV and routine clearance were regarded as an experimental group (EG), and 40 with routine clearance alone were enrolled to a control group (CG). The sputum clearance rate and CPIS score were compared. The safety of NIPPV was evaluated. The clearance treatment cost, hospitalization time and expenses, and the changes of inflammatory factors (IL-6, TNF-α, C-reactive protein (CRP)) were compared before and after treatment. The efficacy of airway clearance after treatment and the risk factors affecting the severity of infection was assessed.

Results: The sputum clearance rate in the EG was higher than that in the CG (P < 0.05). After treatment, the CPIS score of EG was lower (P < 0.05). The hospitalization time and expenses of CG were higher. After treatment, the serum inflammatory factors in CG were higher (P < 0.05), while the clinical efficacy of EG was higher (P < 0.05). Treatment plan, course of disease and diabetes are risk factors for postoperative infection.

Conclusion: NIPPV combined with routine clearance is effective for elderly SAP patients, which can shorten the hospitalization time and reduce the expenses.

Citing Articles

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Hao R, Sun Y, Hu Y Gastroenterology Res. 2024; 17(2):82-89.

PMID: 38716287 PMC: 11073457. DOI: 10.14740/gr1679.

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