Tai Chi Practice Enables Prefrontal Cortex Bilateral Activation and Gait Performance Prioritization During Dual-task Negotiating Obstacle in Older Adults

Background: With aging, the cognitive function of the prefrontal cortex (PFC) declined, postural control weakened, and fall risk increased. As a mind-body exercise, regular Tai Chi practice could improve postural control and effectively prevent falls; however, underlying brain mechanisms remained unclear, which were shed light on by analyzing the effect of Tai Chi on the PFC in older adults by means of functional near-infrared spectroscopy (fNIRS).

Methods: 36 healthy older adults without Tai Chi experience were divided randomly into Tai Chi group and Control group. The experiment was conducted four times per week for 16 weeks; 27 participants remained and completed the experiment. Negotiating obstacle task (NOT) and negotiating obstacle with cognitive task (NOCT) were performed pre- and post-intervention, and Brodmann area 10 (BA10) was detected using fNIRS for hemodynamic response. A three-dimensional motion capture system measured walking speed.

Results: After intervention in the Tai Chi group under NOCT, the HbO concentration change value (ΔHbO) in BA10 was significantly greater (right BA10:  = 0.002, left BA10:  = 0.001), walking speed was significantly faster ( = 0.040), and dual-task cost was significantly lower than pre-intervention ( = 0.047). ΔHbO in BA10 under NOCT was negatively correlated with dual-task cost (right BA10:  = -0.443,  = 0.021, left BA10:  = -0.448,  = 0.019). There were strong negative correlations between ΔHbO and ΔHbR under NOCT either pre-intervention (left PFC  = -0.841,  < 0.001; right PFC  = -0.795,  < 0.001) or post-intervention (left PFC  = -0.842,  < 0.001; right PFC  = -0.744,  < 0.001).

Conclusion: Tai Chi practice might increase the cognitive resources in older adults through the PFC bilateral activation to prioritize gait performance during negotiating obstacles under a dual-task condition.