Detection of Subtypes in Children with Functional Abdominal Pain and Celiac Disease in Çorum, Turkey

Overview

Journal Iran J Parasitol

Publisher Tehran University of Medical Sciences

Specialty Parasitology

Date 2022 Dec 5

PMID 36466032

Authors

Ayse Semra Gureser

Atakan Comba

Djursun Karasartova

Nezahat Kosar

Adem Keskin

Christen Rune Stensvold

Aysegul Taylan-Ozkan

Affiliations

Soon will be listed here.

Abstract

Background: has been associated with various symptoms of the gastrointestinal tract. We aimed to investigate the prevalence of in children with celiac disease (CeD) or functional abdominal pain (FAP) and to evaluate its subtypes (STs) with respect to demographic, socioeconomic and epidemiological factors.

Methods: Overall, 161 fecal samples were collected from healthy children and patients with FAP or CeD in Hitit University Erol Olçok Research and Training Hospital, Corum, Turkey between 2016-2018. Samples were examined using both native-Lugol (NL) and trichrome-stained (TS) smears, and further analyses by PCR and Sanger sequencing were performed. A standard questionnaire was applied to obtain demographic, socioeconomic, epidemiological data.

Results: was found in 10.6% of the total study population. Neither bacteria nor any other parasites were found, except for one (0.6%) in the CeD group. The presence/absence of the parasite was not found to be associated with demographic, socioeconomic and epidemiological factors. was detected in 11.5% (6/52) of the CeD, 7.7% (4/52) of the FAP, and 12.3% (7/57) of the healthy group. Diagnostic methods were similar in terms of detection (= 0.671), and there was fair agreement between the NL, TS and PCR (Fleiss' Kappa=0.847, =0.001). ST2 (42.8%) and ST3 (35.7%) were the predominant STs followed by ST1 (21.4%).

Conclusion: We observed no difference between study groups in terms of prevalence. ST1, ST2 and ST3 subtypes were detected. prevalence and STs were not related to any of the demographic, socioeconomic and epidemiological factors.

Citing Articles

Investigation of intestinal parasites by conventional and molecular methods in children with gastrointestinal system complaints.

Ozkan-Ahmetoglu M, Demirel F, Tasar M, Dinc B, Sarzhanov F, Dogruman-Al F Parasitol Res. 2023; 122(6):1361-1370.

PMID: 37036521 DOI: 10.1007/s00436-023-07836-0.

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