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Validating Emergency Department Cardioversion Procedures in Provincial Administrative Data in Ontario, Canada

Overview
Journal PLoS One
Date 2022 Dec 1
PMID 36454739
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Abstract

Background: Cardioversion of acute-onset atrial fibrillation (AF) via electrical or pharmacological means is a common procedure performed in many emergency departments. While these procedures appear to be very safe, the rarity of subsequent adverse outcomes such as stroke would require huge sample sizes to confirm that conclusion. Big data can supply such sample sizes.

Objective: We aimed to validate several potential codes for successful emergency department cardioversion of AF patients.

Methods: This study combined 3 observational datasets of emergency department AF visits seen at one of 26 hospitals in Ontario, Canada, between 2008 and 2012. We linked patients who were eligible for emergency department cardioversion to several province-wide health administrative datasets to search for the associated cardioversion billing and procedural codes. Using the observational data as the gold standard for successful cardioversion, we calculated the test characteristics of a billing code (Z437) and of procedural codes 1.HZ.09JAFS and 1.HZ.09JAJS. Both include pharmacological and electrical cardioversions, as well as unsuccessful attempts; the latter is <10% using electricity (in Canada, standard practice is to proceed to electrical cardioversion if pharmacological cardioversion is unsuccessful).

Results: Of 4557 unique patients in the three datasets, 2055 (45.1%) were eligible for cardioversion. Nine hundred thirty-three (45.4%) of these were successfully cardioverted to normal sinus rhythm. The billing code had slightly better test characteristics overall than the procedural codes. Positive predictive value (PPV) of a billing was 89.8% (95% CI, 87.0-92.2), negative predictive value (NPV) 70.5% (95% CI, 68.1-72.8), sensitivity 52.1% (95% CI, 48.8-55.3), and specificity 95.1% (95% CI, 93.7-96.3).

Conclusions: AF patients who have been successfully cardioverted in an emergency department can be identified with high PPV and specificity using a billing code. Studies that require high sensitivity for cardioversion should consider other methods to identify cardioverted patients.

References
1.
Oral H, Souza J, Michaud G, Knight B, Goyal R, Strickberger S . Facilitating transthoracic cardioversion of atrial fibrillation with ibutilide pretreatment. N Engl J Med. 1999; 340(24):1849-54. DOI: 10.1056/NEJM199906173402401. View

2.
January C, Samuel Wann L, Calkins H, Chen L, Cigarroa J, Cleveland Jr J . 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the.... J Am Coll Cardiol. 2019; 74(1):104-132. DOI: 10.1016/j.jacc.2019.01.011. View

3.
Andrade J, Mitchell L . Periprocedural Anticoagulation for Cardioversion of Acute Onset Atrial Fibrillation and Flutter: Evidence Base for Current Guidelines. Can J Cardiol. 2019; 35(10):1301-1310. DOI: 10.1016/j.cjca.2019.06.006. View

4.
Stiell I, Clement C, Rowe B, Brison R, Wyse D, Birnie D . Outcomes for Emergency Department Patients With Recent-Onset Atrial Fibrillation and Flutter Treated in Canadian Hospitals. Ann Emerg Med. 2017; 69(5):562-571.e2. DOI: 10.1016/j.annemergmed.2016.10.013. View

5.
Hall R, Mondor L, Porter J, Fang J, Kapral M . Accuracy of Administrative Data for the Coding of Acute Stroke and TIAs. Can J Neurol Sci. 2016; 43(6):765-773. DOI: 10.1017/cjn.2016.278. View