Endoscopically Observed Outer Membrane of Chronic Subdural Hematoma After Endovascular Embolization of Middle Meningeal Artery

Overview

Journal Surg Neurol Int

Specialty Neurology

Date 2022 Nov 30

PMID 36447896

Authors

Sadahiro Nomura

Kohei Haji

Yuichi Fujiyama

Takuma Nishimoto

Fumiaki Oka

Hideyuki Ishihara

Affiliations

Soon will be listed here.

Abstract

Background: Embolization of the middle meningeal artery (MMA) has been established for chronic subdural hematoma (CSDH). Neuroendoscopic observation of the outer membrane of the hematoma was carried out after embolization. The treatment mechanism of embolization is discussed, focusing on the vasculature and inflammation of the membrane.

Methods: Four patients with recurrent CSDH were included in this study. The MMA was embolized using Embosphere particles in three patients. The outer membrane was observed with normal and narrow band images (NBIs).

Results: The net-like vessels were not obstructed in the whole area of the outer membrane, but in a patchy fashion of embolized areas surrounded by nonembolized areas. In two patients, the nonembolized areas showed a hemorrhagic inflammatory red color. Histopathological examination confirmed hypertrophic dura with leukocyte infiltration. Dilated dural arteries and proliferated sinusoid arteries were located in the deep and superficial border cell layers. These arteries were visualized as green and brown on NBI, respectively. In the embolized area, the red membrane turned pink, indicating ischemia and subsiding inflammatory hyperemia. In the third patient, the outer membrane was white in both the nonembolized and embolized areas in endoscopic view, and the net-like vessels were sparse in both endoscopy and histology, indicating a scar inflammatory phase. The membrane transition was not observed in the patient that did not undergo embolization.

Conclusion: Endoscopic observation revealed that embolization of the MMA blocked both the dural and sinusoidal arteries. Ischemic transformation causing the suppression of inflammation of the outer membrane is a suggested mechanism of MMA embolization.

Citing Articles

Extensive Roles and Technical Advances of Middle Meningeal Artery Embolization for Chronic Subdural Hematoma.

Nakagawa I, Kotsugi M, Yokoyama S, Maeoka R, Tamura K, Takeshima Y Neurol Med Chir (Tokyo). 2023; 63(8):327-333.

PMID: 37286481 PMC: 10482489. DOI: 10.2176/jns-nmc.2023-0017.

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