Effects of Phytoestrogens on Reproductive Organ Health
Overview
Affiliations
Phytoestrogens are non-steroidal, polyphenolic compounds that are derived from plants and have biological properties similar to those of human estrogens. Their bioactivity, which is based on the core ring system, is caused by their structural resemblance to estrogen. Flavonoids, coumestans, lignans, and stilbenes are the four major categories into which they can be divided. They are structurally and functionally related to ovarian and placental estrogens, which are essential in female reproductive processes. Phytoestrogens are present in numerous dietary supplements and find application in hormone replacement therapy as an alternative to synthetic hormones. In addition, they provide health benefits for osteoporosis, heart disease, breast cancer, and prostate cancer. There is a growing interest in using phytoestrogen as preventative medicine in the form of nutraceuticals. This literature provides comprehensive information about the types, sources, and biological actions of phytoestrogens in the reproductive system.
Role of Seed Therapy on Estrous and Non-Estrous Cycle in Healthy Female Rats.
Majeed I, Nisa M, Rahim M, Ramadan M, Al-Asmari F, Alissa M Food Sci Nutr. 2025; 13(1):e4692.
PMID: 39807431 PMC: 11725979. DOI: 10.1002/fsn3.4692.
Qiu Z, Huang E, Li Y, Du J, Kan J BMC Womens Health. 2024; 24(1):652.
PMID: 39709418 PMC: 11662844. DOI: 10.1186/s12905-024-03488-z.
A diet enriched with fruits improves the female rats' reproductive system.
Dogani M, Askari N, Hesari A J Tradit Complement Med. 2024; 14(3):335-342.
PMID: 38707920 PMC: 11068987. DOI: 10.1016/j.jtcme.2023.09.004.
Hu H, Zhang J, Xin X, Jin Y, Zhu Y, Zhang H J Ovarian Res. 2024; 17(1):46.
PMID: 38378652 PMC: 10877904. DOI: 10.1186/s13048-024-01369-5.
The Role of Genistein in Mammalian Reproduction.
Guelfi G, Pasquariello R, Anipchenko P, Capaccia C, Pennarossa G, Brevini T Molecules. 2023; 28(21).
PMID: 37959856 PMC: 10647478. DOI: 10.3390/molecules28217436.