» Articles » PMID: 36432188

Diversity: Species, Dispositions, Secondary Metabolites, and Bioactivities

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2022 Nov 26
PMID 36432188
Authors
Affiliations
Soon will be listed here.
Abstract

species have gained attention thanks to their structurally complex and biologically active secondary metabolites. In past decades, several new secondary metabolites were isolated and identified. Their bioactivities were tested, including anticancer, antifungal, antibacterial, and nematicidal activity. Since the previous review published in 2014, new secondary metabolites were isolated and identified from species and unidentified strains. This review gathered published articles from 2014 to 2021 and focused on 239 new secondary metabolites and their bioactivities. To date, 384 species have been discovered in diverse ecological habitats, with the majority of them unstudied. Some may contain secondary metabolites with unique bioactivities that might benefit pharmacology.

Citing Articles

Comparative Diversity and Functional Traits of Fungal Endophytes in Response to Elevated Mineral Content in a Mangrove Ecosystem.

Jacob J, Witzel K, Cruz T J Fungi (Basel). 2023; 9(12).

PMID: 38132787 PMC: 10744541. DOI: 10.3390/jof9121186.


Bioactive ambuic acid congeners from endophytic fungus Pestalotiopsis trachicarpicola SC-J551.

Dong F, Jiang Z, Wu P, Duan F, Xue J, Tan H J Antibiot (Tokyo). 2023; 77(1):21-29.

PMID: 37957338 DOI: 10.1038/s41429-023-00674-3.

References
1.
Ding G, Qi Y, Liu S, Guo L, Chen X . Photipyrones A and B, new pyrone derivatives from the plant endophytic fungus Pestalotiopsis photiniae. J Antibiot (Tokyo). 2012; 65(5):271-3. DOI: 10.1038/ja.2012.14. View

2.
Bruckner D, Hafner F, Li V, Schmeck C, Telser J, Vakalopoulos A . Dibenzodioxocinones--a new class of CETP inhibitors. Bioorg Med Chem Lett. 2005; 15(15):3611-4. DOI: 10.1016/j.bmcl.2005.05.073. View

3.
Wei M, Li D, Shao C, Deng D, Wang C . (±)-Pestalachloride D, an antibacterial racemate of chlorinated benzophenone derivative from a soft coral-derived fungus Pestalotiopsis sp. Mar Drugs. 2013; 11(4):1050-60. PMC: 3705387. DOI: 10.3390/md11041050. View

4.
Feng L, Han J, Wang J, Zhang A, Miao Y, Tan N . Pestalopyrones A-D, four tricyclic pyrone derivatives from the endophytic fungus Pestalotiopsis neglecta S3. Phytochemistry. 2020; 179:112505. DOI: 10.1016/j.phytochem.2020.112505. View

5.
Liu S, Dai H, Makhloufi G, Heering C, Janiak C, Hartmann R . Cytotoxic 14-Membered Macrolides from a Mangrove-Derived Endophytic Fungus, Pestalotiopsis microspora. J Nat Prod. 2016; 79(9):2332-40. DOI: 10.1021/acs.jnatprod.6b00473. View