Minimal Change Disease Caused by Polycythemia Vera: A Case Report

Overview

Journal World J Clin Cases

Publisher Baishideng Publishing Group

Specialty General Medicine

Date 2022 Nov 21

PMID 36405274

Authors

Li Xu

Li-Li Lu

Jian-Dong Gao

Affiliations

Soon will be listed here.

Abstract

Background: Polycythemia vera (PV), often attributed to the JAK2 V617F mutation, is characterized by enhanced red blood cell counts in the peripheral blood. PV-associated renal disease is clinically rare; to date, there have been reports of other chronic kidney diseases related to PV, but no reports on PV-associated minimal change disease.

Case Summary: A 37-year-old man presented with proteinuria and high red blood cell count on January 4, 2021. The patient underwent bone marrow and renal biopsies, then was subsequently diagnosed with PV and minimal change in disease. Hydroxyurea was administered and proteinuria remission was achieved. The patient's last visit was on April 14, 2022.

Conclusion: We inferred that there may be a causal relationship between PV and minimal change disease.

Citing Articles

A case report and literature review of IgA nephropathy presenting as nephrotic syndrome in polycythemia vera.

Rajasekar R, Nandakumar R, Singhvi S, Mathew G, Jayaprakash V, Mythili K CEN Case Rep. 2024; 13(6):495-498.

PMID: 38643434 PMC: 11608193. DOI: 10.1007/s13730-024-00879-x.

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