Mortality and Quality of Life with Chronic Kidney Disease: A Five-Year Cohort Study with a Sample Initially Receiving Peritoneal Dialysis

Overview

Journal Healthcare (Basel)

Specialty Health Services

Date 2022 Nov 11

PMID 36360484

Authors

Miquel Sitjar-Suner

Rosa Suner-Soler

Carme Bertran-Noguer

Afra Masia-Plana

Natalia Romero-Marull

Gloria Reig-Garcia

Francesc Alos

Josefina Patino-Maso

Affiliations

Soon will be listed here.

Abstract

Objectives: To study the quality of life, morbidity and mortality of people receiving renal replacement therapy over a five-year period.

Design: A longitudinal multicentre study of a cohort of people with chronic kidney disease.

Methods: Patients from the Girona health area receiving peritoneal dialysis were studied, gathering data on sociodemographic and clinical variables through an ad hoc questionnaire, quality of life using the SF-36 questionnaire, and social support with the MOS scale.

Results: Mortality was 47.2%. Physical functioning was the variable that worsened most in comparison with the first measurement ( = 0.035). Those receiving peritoneal dialysis ( = 0.068) and transplant recipients ( = 0.083) had a better general health perception. The social functioning of transplant recipients improved ( = 0.008).

Conclusions: People with chronic kidney disease had a high level of mortality. The dimension of physical functioning worsens over the years. Haemodialysis is the therapy that most negatively effects general health perception. Kidney transplantation has a positive effect on the dimensions of energy/vitality, social functioning and general health perception.

Citing Articles

Quality of Life and Related Factors in Patients Undergoing Renal Replacement Therapy at the Hospital General Universitario de Ciudad Real: Cross Sectional Descriptive Observational Study.

Berenguer-Martinez J, Bernal-Celestino R, Leon-Martin A, Gonzalez-Moro M, Fernandez-Calvo N, Arias-Del-Campo L J Clin Med. 2023; 12(6).

PMID: 36983250 PMC: 10058206. DOI: 10.3390/jcm12062250.

References

Olivera L, Okuno M, Barbosa D, Sesso R, Junior G, Pessoa J . Quality of life and spirituality of patients with chronic kidney disease: pre- and post-transplant analysis. Rev Bras Enferm. 2020; 73 Suppl 5:e20190408. DOI: 10.1590/0034-7167-2019-0408. View

Dabrowska-Bender M, Dykowska G, Zuk W, Milewska M, Staniszewska A . The impact on quality of life of dialysis patients with renal insufficiency. Patient Prefer Adherence. 2018; 12:577-583. PMC: 5916456. DOI: 10.2147/PPA.S156356. View

Yang C, Harris D, Luyckx V, Nangaku M, Hou F, Garcia G . Global case studies for chronic kidney disease/end-stage kidney disease care. Kidney Int Suppl (2011). 2020; 10(1):e24-e48. PMC: 7031689. DOI: 10.1016/j.kisu.2019.11.010. View

Fu R, Kim S, de Oliveira C, Coyte P . An instrumental variable approach confirms that the duration of pretransplant dialysis has a negative impact on the survival of kidney transplant recipients and quantifies the risk. Kidney Int. 2019; 96(2):450-459. DOI: 10.1016/j.kint.2019.03.007. View

De Pasquale C, Pistorio M, Veroux M, Indelicato L, Biffa G, Bennardi N . Psychological and Psychopathological Aspects of Kidney Transplantation: A Systematic Review. Front Psychiatry. 2020; 11:106. PMC: 7066324. DOI: 10.3389/fpsyt.2020.00106. View

Lin Q, Zhao S, Gao D, Lou Y, Yang S, Musa S . A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action. Int J Infect Dis. 2020; 93:211-216. PMC: 7102659. DOI: 10.1016/j.ijid.2020.02.058. View

Klinger M, Madziarska K . Mortality predictor pattern in hemodialysis and peritoneal dialysis in diabetic patients. Adv Clin Exp Med. 2018; 28(1):133-135. DOI: 10.17219/acem/76751. View

Ratajczak A, Lange-Ratajczak M, Bobkiewicz A, Studniarek A . Surgical Management of Complications with Peritoneal Dialysis. Semin Dial. 2016; 30(1):63-68. DOI: 10.1111/sdi.12538. View

Zazzeroni L, Pasquinelli G, Nanni E, Cremonini V, Rubbi I . Comparison of Quality of Life in Patients Undergoing Hemodialysis and Peritoneal Dialysis: a Systematic Review and Meta-Analysis. Kidney Blood Press Res. 2017; 42(4):717-727. DOI: 10.1159/000484115. View

10.

Lo C, Toyama T, Wang Y, Lin J, Hirakawa Y, Jun M . Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease. Cochrane Database Syst Rev. 2018; 9:CD011798. PMC: 6513625. DOI: 10.1002/14651858.CD011798.pub2. View

11.

Ye H, Zhou Q, Fan L, Guo Q, Mao H, Huang F . The impact of peritoneal dialysis-related peritonitis on mortality in peritoneal dialysis patients. BMC Nephrol. 2017; 18(1):186. PMC: 5460447. DOI: 10.1186/s12882-017-0588-4. View

12.

Banshodani M, Kawanishi H, Moriishi M, Shintaku S, Tsuchiya S . Association between Dialysis Modality and Cardiovascular Diseases: A Comparison between Peritoneal Dialysis and Hemodialysis. Blood Purif. 2019; 49(3):302-309. DOI: 10.1159/000504040. View

13.

de Arriba G, Avila G, Guinea M, Alia I, Herruzo J, Ruiz B . Mortality of hemodialysis patients is associated with their clinical situation at the start of treatment. Nefrologia (Engl Ed). 2022; 41(4):461-466. DOI: 10.1016/j.nefroe.2021.10.006. View

14.

Feng X, Wen Y, Peng F, Wang N, Zhan X, Wu X . Association between aminotransferase/alanine aminotransferase ratio and cardiovascular disease mortality in patients on peritoneal dialysis: a multi-center retrospective study. BMC Nephrol. 2020; 21(1):209. PMC: 7268679. DOI: 10.1186/s12882-020-01840-7. View

15.

Martini A, Ammirati A, Garcia C, Andrade C, Portela O, Cendoroglo M . Evaluation of quality of life, physical, and mental aspects in longevous patients with chronic kidney disease. Int Urol Nephrol. 2018; 50(4):725-731. DOI: 10.1007/s11255-018-1813-1. View

16.

Chang Y, Hwang J, Hung S, Tsai M, Wu J, Sung J . Cost-effectiveness of hemodialysis and peritoneal dialysis: A national cohort study with 14 years follow-up and matched for comorbidities and propensity score. Sci Rep. 2016; 6:30266. PMC: 4962092. DOI: 10.1038/srep30266. View

17.

Hiramatsu T, Okumura S, Asano Y, Mabuchi M, Iguchi D, Furuta S . Quality of Life and Emotional Distress in Peritoneal Dialysis and Hemodialysis Patients. Ther Apher Dial. 2019; 24(4):366-372. DOI: 10.1111/1744-9987.13450. View

18.

Rhee C, Chou J, Kalantar-Zadeh K . Dialysis Prescription and Sudden Death. Semin Nephrol. 2018; 38(6):570-581. PMC: 6392037. DOI: 10.1016/j.semnephrol.2018.08.003. View

19.

Chuasuwan A, Pooripussarakul S, Thakkinstian A, Ingsathit A, Pattanaprateep O . Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis. Health Qual Life Outcomes. 2020; 18(1):191. PMC: 7302145. DOI: 10.1186/s12955-020-01449-2. View

20.

Esposito S, Principi N, Leung C, Migliori G . Universal use of face masks for success against COVID-19: evidence and implications for prevention policies. Eur Respir J. 2020; 55(6). PMC: 7191114. DOI: 10.1183/13993003.01260-2020. View