An Improved Detection Algorithm for Ischemic Stroke NCCT Based on YOLOv5

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2022 Nov 11

PMID 36359435

Authors

Lifeng Zhang

Hongyan Cui

Anming Hu

Jiadong Li

Yidi Tang

Roy Elmer Welsch

Affiliations

Soon will be listed here.

Abstract

Cerebral stroke (CS) is a heterogeneous syndrome caused by multiple disease mechanisms. Ischemic stroke (IS) is a subtype of CS that causes a disruption of cerebral blood flow with subsequent tissue damage. Noncontrast computer tomography (NCCT) is one of the most important IS detection methods. It is difficult to select the features of IS CT within computational image analysis. In this paper, we propose AC-YOLOv5, which is an improved detection algorithm for IS. The algorithm amplifies the features of IS via an NCCT image based on adaptive local region contrast enhancement, which then detects the region of interest via YOLOv5, which is one of the best detection algorithms at present. The proposed algorithm was tested on two datasets, and seven control group experiments were added, including popular detection algorithms at present and other detection algorithms based on image enhancement. The experimental results show that the proposed algorithm has a high accuracy (94.1% and 91.7%) and recall (85.3% and 88.6%) rate; the recall result is especially notable. This proves the excellent performance of the accuracy, robustness, and generalizability of the algorithm.

References

Wardlaw J, Mielke O . Early signs of brain infarction at CT: observer reliability and outcome after thrombolytic treatment--systematic review. Radiology. 2005; 235(2):444-53. DOI: 10.1148/radiol.2352040262. View

Warren D, Musson R, Connolly D, Griffiths P, Hoggard N . Imaging in acute ischaemic stroke: essential for modern stroke care. Postgrad Med J. 2010; 86(1017):409-18. DOI: 10.1136/pgmj.2010.097931. View

Fonarow G, Smith E, Saver J, Reeves M, Bhatt D, Grau-Sepulveda M . Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes. Circulation. 2011; 123(7):750-8. DOI: 10.1161/CIRCULATIONAHA.110.974675. View

Anderson D . Koro: the genital retraction symptom after stroke. Br J Psychiatry. 1990; 157:142-4. DOI: 10.1192/bjp.157.1.142. View

Shen D, Wu G, Suk H . Deep Learning in Medical Image Analysis. Annu Rev Biomed Eng. 2017; 19:221-248. PMC: 5479722. DOI: 10.1146/annurev-bioeng-071516-044442. View

Kuang H, Menon B, Qiu W . Semi-automated infarct segmentation from follow-up noncontrast CT scans in patients with acute ischemic stroke. Med Phys. 2019; 46(9):4037-4045. DOI: 10.1002/mp.13703. View

Rudkin S, Cerejo R, Tayal A, Goldberg M . Imaging of acute ischemic stroke. Emerg Radiol. 2018; 25(6):659-672. DOI: 10.1007/s10140-018-1623-x. View

Chiriboga M, Green C, Hastman D, Mathur D, Wei Q, Diaz S . Rapid DNA origami nanostructure detection and classification using the YOLOv5 deep convolutional neural network. Sci Rep. 2022; 12(1):3871. PMC: 8907326. DOI: 10.1038/s41598-022-07759-3. View

Bousser M, Eschwege E, Haguenau M, Lefaucconnier J, Thibult N, Touboul D . "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia. Stroke. 1983; 14(1):5-14. DOI: 10.1161/01.str.14.1.5. View

10.

Wang J, Tan D, Liu J, Wu J, Huang F, Xiong H . Merging Multiphase CTA Images and Training Them Simultaneously with a Deep Learning Algorithm Could Improve the Efficacy of AI Models for Lateral Circulation Assessment in Ischemic Stroke. Diagnostics (Basel). 2022; 12(7). PMC: 9315590. DOI: 10.3390/diagnostics12071562. View

11.

Cipolla M, Liebeskind D, Chan S . The importance of comorbidities in ischemic stroke: Impact of hypertension on the cerebral circulation. J Cereb Blood Flow Metab. 2018; 38(12):2129-2149. PMC: 6282213. DOI: 10.1177/0271678X18800589. View

12.

Markus H . Cerebral perfusion and stroke. J Neurol Neurosurg Psychiatry. 2004; 75(3):353-61. PMC: 1738983. DOI: 10.1136/jnnp.2003.025825. View

13.

Ren S, He K, Girshick R, Sun J . Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks. IEEE Trans Pattern Anal Mach Intell. 2016; 39(6):1137-1149. DOI: 10.1109/TPAMI.2016.2577031. View

14.

Thomalla G, Boutitie F, Fiebach J, Simonsen C, Pedraza S, Lemmens R . Clinical characteristics of unknown symptom onset stroke patients with and without diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch. Int J Stroke. 2017; 13(1):66-73. DOI: 10.1177/1747493017706245. View

15.

Doi K . Computer-aided diagnosis in medical imaging: historical review, current status and future potential. Comput Med Imaging Graph. 2007; 31(4-5):198-211. PMC: 1955762. DOI: 10.1016/j.compmedimag.2007.02.002. View

16.

Soun J, Chow D, Nagamine M, Takhtawala R, Filippi C, Yu W . Artificial Intelligence and Acute Stroke Imaging. AJNR Am J Neuroradiol. 2020; 42(1):2-11. PMC: 7814792. DOI: 10.3174/ajnr.A6883. View

17.

Gibson C . Cerebral ischemic stroke: is gender important?. J Cereb Blood Flow Metab. 2013; 33(9):1355-61. PMC: 3764377. DOI: 10.1038/jcbfm.2013.102. View

18.

Das J, G K R . Post stroke depression: The sequelae of cerebral stroke. Neurosci Biobehav Rev. 2018; 90:104-114. DOI: 10.1016/j.neubiorev.2018.04.005. View

19.

Lansberg M, Albers G, Beaulieu C, Marks M . Comparison of diffusion-weighted MRI and CT in acute stroke. Neurology. 2000; 54(8):1557-61. DOI: 10.1212/wnl.54.8.1557. View

20.

Mikhail P, Le M, Mair G . Computational Image Analysis of Nonenhanced Computed Tomography for Acute Ischaemic Stroke: A Systematic Review. J Stroke Cerebrovasc Dis. 2020; 29(5):104715. DOI: 10.1016/j.jstrokecerebrovasdis.2020.104715. View