» Articles » PMID: 36358840

Role of the PP2A Pathway in Cholangiocarcinoma: State of the Art and Future Perspectives

Overview
Journal Cancers (Basel)
Publisher MDPI
Specialty Oncology
Date 2022 Nov 11
PMID 36358840
Authors
Affiliations
Soon will be listed here.
Abstract

Cholangiocarcinoma represents a heterogeneous disease at both a clinical and molecular level [...].

Citing Articles

Circular RNA Vav3 mediated ALV-J inhibition of autophagy by modulating the gga-miR-375/CIP2A axis and activating AKT.

Chen L, Xu H, Liu R, Yao Z, Xie Q, Zhang X Poult Sci. 2025; 104(4):104923.

PMID: 39987600 PMC: 11904538. DOI: 10.1016/j.psj.2025.104923.


Cholangiocarcinoma Malignant Traits Are Promoted by Schwann Cells through TGFβ Signaling in a Model of Perineural Invasion.

de Franchis V, Petrungaro S, Pizzichini E, Camerini S, Casella M, Somma F Cells. 2024; 13(5.

PMID: 38474330 PMC: 10930666. DOI: 10.3390/cells13050366.


A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of .

Omella J, Cortesi E, Verbinnen I, Remmerie M, Wu H, Cubero F Cancers (Basel). 2023; 15(16).

PMID: 37627221 PMC: 10453342. DOI: 10.3390/cancers15164193.

References
1.
Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R . FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling. BMC Cancer. 2014; 14:783. PMC: 4221672. DOI: 10.1186/1471-2407-14-783. View

2.
Halder R, Amaraneni A, Shroff R . Cholangiocarcinoma: a review of the literature and future directions in therapy. Hepatobiliary Surg Nutr. 2022; 11(4):555-566. PMC: 9396092. DOI: 10.21037/hbsn-20-396. View

3.
Cristobal I, Rincon R, Manso R, Madoz-Gurpide J, Carames C, Del Puerto-Nevado L . Hyperphosphorylation of PP2A in colorectal cancer and the potential therapeutic value showed by its forskolin-induced dephosphorylation and activation. Biochim Biophys Acta. 2014; 1842(9):1823-9. DOI: 10.1016/j.bbadis.2014.06.032. View

4.
Eichhorn P, Creyghton M, Bernards R . Protein phosphatase 2A regulatory subunits and cancer. Biochim Biophys Acta. 2008; 1795(1):1-15. DOI: 10.1016/j.bbcan.2008.05.005. View

5.
Westermarck J, Hahn W . Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends Mol Med. 2008; 14(4):152-60. DOI: 10.1016/j.molmed.2008.02.001. View