Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study

Overview

Journal Open Forum Infect Dis

Specialty Infectious Diseases

Date 2022 Nov 2

PMID 36320192

Authors

Arjun Chandna

Raman Mahajan

Priyanka Gautam

Lazaro Mwandigha

Pragya Kumar

George M Varghese

Constantinos Koshiaris

Yoel Lubell

Sakib Burza

Affiliations

Soon will be listed here.

Abstract

Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.

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