Bioactive Molecules from Plants: Discovery and Pharmaceutical Applications

Overview

Journal Pharmaceutics

Publisher MDPI

Date 2022 Oct 27

PMID 36297551

Authors

Maria Camilla Bergonzi

Charles M Heard

Javier Garcia-Pardo

Affiliations

Soon will be listed here.

Abstract

The plant kingdom is one of the richest sources of bioactive compounds with pharmaceutical potential [...].

Citing Articles

Plant Protease Inhibitors as Emerging Antimicrobial Peptide Agents: A Comprehensive Review.

Parisi M, Ozon B, Vera Gonzalez S, Garcia-Pardo J, Obregon W Pharmaceutics. 2024; 16(5).

PMID: 38794245 PMC: 11125377. DOI: 10.3390/pharmaceutics16050582.

Medicinal Plants as Therapeutic Alternatives to Combat : A Comprehensive Review.

Gautam S, Qureshi K, Jameel Pasha S, Dhanasekaran S, Aspatwar A, Parkkila S Antibiotics (Basel). 2023; 12(3).

PMID: 36978408 PMC: 10044459. DOI: 10.3390/antibiotics12030541.

References

Kello M, Kuruc T, Petrova K, Goga M, Michalova Z, Coma M . Pro-Apoptotic Potential of (L.) Extract and Isolated Physodic Acid in Acute Lymphoblastic Leukemia Model In Vitro. Pharmaceutics. 2021; 13(12). PMC: 8703293. DOI: 10.3390/pharmaceutics13122173. View

Merlani M, Scheibel D, Barbakadze V, Gogilashvili L, Amiranashvili L, Geronikaki A . Enzymatic Synthesis and Antimicrobial Activity of Oligomer Analogues of Medicinal Biopolymers from Comfrey and Other Species of the Boraginaceae Family. Pharmaceutics. 2022; 14(1). PMC: 8779701. DOI: 10.3390/pharmaceutics14010115. View

Filipiuc L, Ababei D, Alexa-Stratulat T, Pricope C, Bild V, Stefanescu R . Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?. Pharmaceutics. 2021; 13(11). PMC: 8625816. DOI: 10.3390/pharmaceutics13111823. View

Vildanova M, Vishnyakova P, Saidova A, Konduktorova V, Onishchenko G, Smirnova E . Gibberellic Acid Initiates ER Stress and Activation of Differentiation in Cultured Human Immortalized Keratinocytes HaCaT and Epidermoid Carcinoma Cells A431. Pharmaceutics. 2021; 13(11). PMC: 8622727. DOI: 10.3390/pharmaceutics13111813. View

Monchaux de Oliveira C, De Smedt-Peyrusse V, Morael J, Vancassel S, Capuron L, Gaudout D . Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission. Pharmaceutics. 2021; 13(12). PMC: 8709346. DOI: 10.3390/pharmaceutics13122155. View

Neto I, Dominguez-Martin E, Ntungwe E, Reis C, Pesic M, Faustino C . Dehydroabietic Acid Microencapsulation Potential as Biofilm-Mediated Infections Treatment. Pharmaceutics. 2021; 13(6). PMC: 8229915. DOI: 10.3390/pharmaceutics13060825. View

Mattos E, Pereira P, Merida L, Correa A, Freire M, Paschoalin V . Taro Lectin Can Act as a Cytokine-Mimetic Compound, Stimulating Myeloid and T Lymphocyte Lineages and Protecting Progenitors in Murine Bone Marrow. Pharmaceutics. 2021; 13(3). PMC: 8001523. DOI: 10.3390/pharmaceutics13030350. View

Huang C, Liu I, Huang X, Chen H, Chang S, Chang M . Antimelanogenesis Effects of Leaf Extract and Phytochemicals from Ceylon Olive () in Zebrafish Model. Pharmaceutics. 2021; 13(7). PMC: 8309042. DOI: 10.3390/pharmaceutics13071059. View

Chen G, Chang M, Chang S, Ho Y, Chang H . Cytotoxicity and Apoptosis Induction of 6,7-Dehydroroyleanone from Bark Essential Oil in Hepatocellular Carcinoma Cells. Pharmaceutics. 2022; 14(2). PMC: 8880271. DOI: 10.3390/pharmaceutics14020351. View

10.

Nonpanya N, Sanookpan K, Sriratanasak N, Vinayanuwattikun C, Wichadakul D, Sritularak B . Artocarpin Targets Focal Adhesion Kinase-Dependent Epithelial to Mesenchymal Transition and Suppresses Migratory-Associated Integrins in Lung Cancer Cells. Pharmaceutics. 2021; 13(4). PMC: 8071053. DOI: 10.3390/pharmaceutics13040554. View

11.

Chung K, Yoo C, Lee J, Lee H, Park S, Han H . Regulation of ROS-Dependent JNK Pathway by 2'-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells. Pharmaceutics. 2021; 13(11). PMC: 8618870. DOI: 10.3390/pharmaceutics13111794. View

12.

Caroleo M, Plastina P, Fazio A, La Torre C, Manetti F, Cione E . Olive Oil Lipophenols Induce Insulin Secretion in 832/13 β-Cell Models. Pharmaceutics. 2021; 13(7). PMC: 8309142. DOI: 10.3390/pharmaceutics13071085. View

13.

Manganyi M, Tlatsana G, Mokoroane G, Senna K, Mohaswa J, Ntsayagae K . Bulbous Plants : "A Thin Line between Poisonous and Healing Compounds" with Biological Activities. Pharmaceutics. 2021; 13(9). PMC: 8465487. DOI: 10.3390/pharmaceutics13091385. View

14.

Lee D, Kim Y, Chin Y, Kang K . Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells. Pharmaceutics. 2021; 13(7). PMC: 8308983. DOI: 10.3390/pharmaceutics13071082. View

15.

Cotabarren J, Claver S, Payrol J, Garcia-Pardo J, Obregon W . Purification and Characterization of a Novel Thermostable Papain Inhibitor from with Antimicrobial and Anticoagulant Properties. Pharmaceutics. 2021; 13(4). PMC: 8068210. DOI: 10.3390/pharmaceutics13040512. View

16.

Kobryn J, Dalek J, Musial W . The Influence of Selected Factors on the Aqueous Cryptotanshinone Solubility. Pharmaceutics. 2021; 13(7). PMC: 8309180. DOI: 10.3390/pharmaceutics13070992. View

17.

Wikan N, Hankittichai P, Thaklaewphan P, Potikanond S, Nimlamool W . Oxyresveratrol Inhibits TNF-α-Stimulated Cell Proliferation in Human Immortalized Keratinocytes (HaCaT) by Suppressing AKT Activation. Pharmaceutics. 2022; 14(1). PMC: 8781909. DOI: 10.3390/pharmaceutics14010063. View

18.

Landucci E, Bonomolo F, De Stefani C, Mazzantini C, Pellegrini-Giampietro D, Bilia A . Preparation of Liposomal Formulations for Ocular Delivery of Thymoquinone: In Vitro Evaluation in HCEC-2 e HConEC Cells. Pharmaceutics. 2021; 13(12). PMC: 8704629. DOI: 10.3390/pharmaceutics13122093. View

19.

Cotabarren J, Ozon B, Claver S, Garcia-Pardo J, Obregon W . Purification and Identification of Novel Antioxidant Peptides Isolated from Seeds with Anticoagulant Activity. Pharmaceutics. 2021; 13(8). PMC: 8399481. DOI: 10.3390/pharmaceutics13081153. View

20.

Kim M, Lee H, Ji S, Kim S, Hwangbo H, Park S . Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway. Pharmaceutics. 2021; 13(10). PMC: 8540929. DOI: 10.3390/pharmaceutics13101627. View