Role of Nutrients and Foods in Attenuation of Cardiac Remodeling Through Oxidative Stress Pathways

Overview

Journal Antioxidants (Basel)

Date 2022 Oct 27

PMID 36290787

Authors

Taline Lazzarin

Leonardo Rufino Garcia

Danilo Martins

Diego Aparecido Rios Queiroz

Carolina Rodrigues Tonon

Paola da Silva Balin

Bertha Furlan Polegato

Sergio Alberto Rupp de Paiva

Paula Schmidt Azevedo

Marcos Minicucci

Leonardo Zornoff

Affiliations

Soon will be listed here.

Abstract

Cardiac remodeling is defined as a group of molecular, cellular, and interstitial changes that manifest clinically as changes in the heart's size, mass, geometry, and function after different injuries. Importantly, remodeling is associated with increased risk of ventricular dysfunction and heart failure. Therefore, strategies to attenuate this process are critical. Reactive oxygen species and oxidative stress play critical roles in remodeling. Importantly, antioxidative dietary compounds potentially have protective properties against remodeling. Therefore, this review evaluates the role of nutrients and food as modulators of cardiac remodeling.

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