Role of Hyaluronic Acid in Periodontal Therapy (Review)

Overview

Journal Biomed Rep

Specialty Biochemistry

Date 2022 Oct 24

PMID 36278244

Authors

Ashok Bhati

Hytham Fageeh

Wael Ibraheem

Hammam Fageeh

Harneet Chopra

Suman Panda

Affiliations

Soon will be listed here.

Abstract

Hyaluronic acid (HA) is essential for the function of extracellular matrices in both hard and soft periodontal components. HA plays an important role in the mechanisms underlying inflammation and wound healing. HA is located in periodontal tissues in differing amounts, including non-mineralized tissues, such as gingiva and periodontal ligament, and lower levels located in mineralized tissues, such as cementum and alveolar bone. According to preliminary findings, HA exhibits potential in the regulation of periodontal tissue regeneration and in the treatment of periodontal disease. HA promotes symptomatic relief in both marginal gingiva and deeper periodontal tissues. The present review aimed to examine the role of HA in periodontal therapy, and investigate the current literature supporting its use in periodontal regeneration.

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