» Articles » PMID: 36249439

Effect of Coronavirus Disease-2019 Infection on Left Atrial Functions

Overview
Date 2022 Oct 17
PMID 36249439
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: Left atrial (LA) dysfunction is a crucial risk factor for cardiovascular events, and various pathologies may affect LA function. Coronavirus disease-2019 (COVID-19) is an ongoing global pandemic causing morbidity and mortality. In the present study, we aimed to evaluate LA functions in patients who recovered from COVID-19.

Methods: Sixty consecutive patients recovered from COVID-19 and 60 healthy individuals as a control group were included in the study. Blood samples and echocardiography measurements were obtained from each subject. The two groups were compared in terms of demographic and echocardiographic characteristics.

Results: In the COVİD-19 group, LA maximum volume (LAV) ( = 0.040), LA pre-A volume (LAVpre-A) ( = 0.014), and LA active emptying fraction ( = 0.027) were higher, while LA passive emptying fraction ( = 0.035) was lower. In addition, left ventricular ejection fraction ( = 0.006) and isovolumetric relaxation time ( = 0.008) were decreased in this group. Although LA volume index was higher in the COVID-19 group, it does not reach statistical significance.

Conclusion: LA functions may be impaired in patients recovered from COVID-19 infection.

Citing Articles

Functional outcomes in post Covid-19 patients with persistent dyspnea: multidisciplinary approach.

Hamdy R, AbdElaziz O, Shamsseldain H, Eltrawy H Int J Cardiovasc Imaging. 2023; 39(6):1115-1122.

PMID: 36879082 PMC: 9988204. DOI: 10.1007/s10554-023-02819-9.

References
1.
Hsiao S, Lin K, Chiou K . Comparison of left atrial volume parameters in detecting left ventricular diastolic dysfunction versus tissue Doppler recordings. Am J Cardiol. 2011; 109(5):748-55. DOI: 10.1016/j.amjcard.2011.10.040. View

2.
Varga Z, Flammer A, Steiger P, Haberecker M, Andermatt R, Zinkernagel A . Endothelial cell infection and endotheliitis in COVID-19. Lancet. 2020; 395(10234):1417-1418. PMC: 7172722. DOI: 10.1016/S0140-6736(20)30937-5. View

3.
Cryer M, Horani T, DiPette D . Diabetes and Hypertension: A Comparative Review of Current Guidelines. J Clin Hypertens (Greenwich). 2015; 18(2):95-100. PMC: 8031521. DOI: 10.1111/jch.12638. View

4.
Shah A, Claggett B, Sweitzer N, Shah S, Anand I, OMeara E . Cardiac structure and function and prognosis in heart failure with preserved ejection fraction: findings from the echocardiographic study of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial. Circ Heart Fail. 2014; 7(5):740-51. PMC: 4916914. DOI: 10.1161/CIRCHEARTFAILURE.114.001583. View

5.
Beltrami M, Palazzuoli A, Padeletti L, Cerbai E, Coiro S, Emdin M . The importance of integrated left atrial evaluation: From hypertension to heart failure with preserved ejection fraction. Int J Clin Pract. 2017; 72(2). DOI: 10.1111/ijcp.13050. View