The Levels of Bioelements in Postmenopausal Women with Metabolic Syndrome

Overview

Journal Nutrients

Date 2022 Oct 14

PMID 36235758

Authors

Anna Maria Cybulska

Daria Schneider-Matyka

Mateusz Bosiacki

Dariusz Chlubek

Mariusz Panczyk

Elzbieta Grochans

Affiliations

Soon will be listed here.

Abstract

(1) Metabolic syndrome is a set of factors that considerably increase the risk of developing atherosclerosis, type 2 diabetes, and their cardiovascular complications. Studies show that menopause and the levels of elements may be significantly associated with increased risk of MetS. The present study evaluated the relationship between element levels (Ca, P, Na, K, Fe, Mg, Cu, Zn, Sr) and the incidence of MetS and concomitant metabolic disorders in peri-menopausal women. (2) The study involved 170 perimenopausal women. The methods used were: survey, anthropometric measurement (WC, height, BMI, WHtR), blood pressure measurement, and biochemical analysis of venous blood (lipid profile, glucose, insulin, HbA1C). (3) The study demonstrated statistically significantly higher WC, WHtR, SBP, and DBP values in women with pre-Mets than in those with Mets and the control group. Significantly higher FPG, TG, LDL, HbA1C, insulin, TG/HDL ratio, and TC/HDL ratio were recorded in the MetS group compared to the rest of respondents. In addition, post hoc analysis revealed statistically significant differences in mean K concentrations between pre-MetS and MetS women. (4) Low blood K levels in perimenopausal women are associated with an increased risk of MetS. Significantly higher Cu levels were observed in overweight women. The concentration of Cu negatively correlates with the values of TC, LDL, and SBP.

Citing Articles

Menopause and metabolic syndrome: anthropometric, lipid, and dietary profiles.

Goncalves V, Lima S Rev Assoc Med Bras (1992). 2024; 70(6):e20231571.

PMID: 39045954 PMC: 11288260. DOI: 10.1590/1806-9282.20231571.

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