Association Between Dietary Inflammatory Index and Oral Cancer Risk: A Systematic Review and Dose-response Meta-analysis

Overview

Journal Front Oncol

Specialty Oncology

Date 2022 Oct 13

PMID 36226053

Authors

Zhicheng Luo

Xidi Zhu

Yingyun Hu

Shipeng Yan

Lizhang Chen

Affiliations

Soon will be listed here.

Abstract

Background: Dietary inflammatory index (DII) has been suggested to be associated with oral cancer risk. However, a quantitative comprehensive assessment of the dose-response relationship has not been reported. We performed a meta-analysis to clarify the risk of oral cancer with DII.

Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science databases for relevant articles published up to 1 March 2022. Fixed- or random-effects models were utilized to estimate the pooled odds ratio (OR) of oral cancer with DII, as appropriate. Restricted cubic splines were used to model the dose-response relationship.

Results: We included five case-control studies involving 1,278 cases and 5,137 controls in the meta-analysis. Risk of oral cancer was increased by 135% with the highest versus lowest DII level [OR: 2.35, 95% confidence interval (CI): 1.88-2.94], and 79% with higher versus lower DII level (OR: 1.79, 95% CI: 1.49-2.15). We found no evidence of a nonlinear dose-response association of DII with oral cancer ( = 0.752), and the risk was increased by 17% (OR: 1.17, 95% CI: 1.05-1.30) with 1 unit increment in DII score.

Conclusion: This meta-analysis suggested that a higher DII score was associated with increased risk of oral cancer. Therefore, reducing pro-inflammatory components and promoting anti-inflammatory components of diet may be effective in the prevention of oral cancer.

Citing Articles

Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy.

Constantin M, Chifiriuc M, Mihaescu G, Vrancianu C, Dobre E, Cristian R Front Oncol. 2024; 13:1273516.

PMID: 38179168 PMC: 10765588. DOI: 10.3389/fonc.2023.1273516.

References

Rodriguez-Molinero J, Del Carmen Miguelanez-Medran B, Puente-Gutierrez C, Delgado-Somolinos E, Carreras-Presas C, Fernandez-Farhall J . Association between Oral Cancer and Diet: An Update. Nutrients. 2021; 13(4). PMC: 8071138. DOI: 10.3390/nu13041299. View

Mehrtash H, Duncan K, Parascandola M, David A, Gritz E, Gupta P . Defining a global research and policy agenda for betel quid and areca nut. Lancet Oncol. 2017; 18(12):e767-e775. DOI: 10.1016/S1470-2045(17)30460-6. View

Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A . Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009; 30(7):1073-81. DOI: 10.1093/carcin/bgp127. View

Alrashdan M, Cirillo N, McCullough M . Oral lichen planus: a literature review and update. Arch Dermatol Res. 2016; 308(8):539-51. DOI: 10.1007/s00403-016-1667-2. View

Jeng J, Wang Y, Chiang B, Lee P, Chan C, Ho Y . Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. Carcinogenesis. 2003; 24(8):1301-15. DOI: 10.1093/carcin/bgg083. View

Rajalalitha P, Vali S . Molecular pathogenesis of oral submucous fibrosis--a collagen metabolic disorder. J Oral Pathol Med. 2005; 34(6):321-8. DOI: 10.1111/j.1600-0714.2005.00325.x. View

Greten F, Grivennikov S . Inflammation and Cancer: Triggers, Mechanisms, and Consequences. Immunity. 2019; 51(1):27-41. PMC: 6831096. DOI: 10.1016/j.immuni.2019.06.025. View

Kurago Z . Etiology and pathogenesis of oral lichen planus: an overview. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016; 122(1):72-80. DOI: 10.1016/j.oooo.2016.03.011. View

Shivappa N, Steck S, Hurley T, Hussey J, Hebert J . Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr. 2013; 17(8):1689-96. PMC: 3925198. DOI: 10.1017/S1368980013002115. View

10.

Farvid M, Sidahmed E, Spence N, Mante Angua K, Rosner B, Barnett J . Consumption of red meat and processed meat and cancer incidence: a systematic review and meta-analysis of prospective studies. Eur J Epidemiol. 2021; 36(9):937-951. DOI: 10.1007/s10654-021-00741-9. View

11.

Liang Y, Jiao H, Qu L, Liu H . Positive association between dietary inflammatory index and gastric cancer risk: A systematic review and meta-analysis. Nutr Cancer. 2019; 72(8):1290-1296. DOI: 10.1080/01635581.2019.1679197. View

12.

Lee Y, Cohet C, Yang Y, Stayner L, Hashibe M, Straif K . Meta-analysis of epidemiologic studies on cigarette smoking and liver cancer. Int J Epidemiol. 2009; 38(6):1497-511. DOI: 10.1093/ije/dyp280. View

13.

Haque M, Harris M, Meghji S, Barrett A . Immunolocalization of cytokines and growth factors in oral submucous fibrosis. Cytokine. 1998; 10(9):713-9. DOI: 10.1006/cyto.1997.0342. View

14.

Li Y, Gu M, Jing F, Cai S, Bao C, Wang J . Association between physical activity and all cancer mortality: Dose-response meta-analysis of cohort studies. Int J Cancer. 2015; 138(4):818-32. DOI: 10.1002/ijc.29828. View

15.

Bao X, Chen F, Lin J, Chen Q, Chen L, Wang R . Association between dietary inflammatory index and the risk of oral cancer in the southeast of China. Eur J Clin Nutr. 2019; 74(6):938-944. DOI: 10.1038/s41430-019-0507-9. View

16.

Khan S, Chatra L, Prashanth S, Veena K, Rao P . Pathogenesis of oral submucous fibrosis. J Cancer Res Ther. 2012; 8(2):199-203. DOI: 10.4103/0973-1482.98970. View

17.

Aggarwal B, Vijayalekshmi R, Sung B . Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe. Clin Cancer Res. 2009; 15(2):425-30. DOI: 10.1158/1078-0432.CCR-08-0149. View

18.

Hua R, Liang G, Yang F . Meta-analysis of the association between dietary inflammatory index (DII) and upper aerodigestive tract cancer risk. Medicine (Baltimore). 2020; 99(17):e19879. PMC: 7220683. DOI: 10.1097/MD.0000000000019879. View

19.

Shivappa N, Hebert J, Marcos A, Diaz L, Gomez S, Nova E . Association between dietary inflammatory index and inflammatory markers in the HELENA study. Mol Nutr Food Res. 2016; 61(6). PMC: 5517083. DOI: 10.1002/mnfr.201600707. View

20.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009; 6(7):e1000097. PMC: 2707599. DOI: 10.1371/journal.pmed.1000097. View