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Three-year Clinical Outcomes of Phacoemulsification Combined with Excisional Goniotomy Using the Kahook Dual Blade for Cataract and Open-angle Glaucoma in Saudi Arabia

Overview
Specialty Ophthalmology
Date 2022 Oct 10
PMID 36211318
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Abstract

Purpose: The aim of this study was to describe the changes in intraocular pressure (IOP), IOP-reducing drugs, and visual acuity (VA) through up to 3 years of follow-up in patients undergoing combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade (KDB-phaco) by a single surgeon in Saudi Arabia.

Methods: The health records of 55 eyes of 47 patients undergoing KDB-phaco by a single surgeon were reviewed. Data were extracted from visits occurring preoperatively ( = 55), intraoperatively ( = 55), and 1-day ( = 55), 2 weeks ( = 55), 4-6 weeks ( = 49), 2-3 months ( = 55), and 6 ( = 55), 9 ( = 55), 12 ( = 55), 18 ( = 49), 24 ( = 46), and 36 months ( = 16) postoperatively. Data collection included IOP, IOP-lowering medications, and VA at each time point. Adverse events were also collected. Paired -tests were used to compare IOP, medications, and VA at each time point to preoperative values.

Results: Mean (standard error) baseline IOP was 20.4 (0.7) mmHg and through up to 36 months of follow-up (minimum 12 months, mean 26.1 [1.0] months) ranged from 13.6 to 14.1 mmHg; significant reductions ( < 0.0007) of 5.7-7.0 mmHg (23.0%-29.5%) were achieved at every time point. Medications were reduced from 3.2 (0.1) to 0.2-2.0 (reductions of 1.2-3.1 medications [50.0%-94.9%]; < 0.0001 at every time point). At months 24 and 36, the mean IOP was 13.9 (0.3) and 13.9 (0.5) mmHg and mean medications were 1.4 (0.2) and 2.0 (0.4). Mean logMAR VA improved from 1.0 (0.1) preoperatively to (0.2 [0.0]; < 0.001) by month 6 and remained stable thereafter through the duration of follow-up.

Conclusion: KDB-phaco significantly lowered IOP approximately 30% by day 1 with consistency and durability through 3 years. Medication use was reduced by >50% through 36 months. Mean logMAR VA improved from 1.0 to 0.2 (Snellen equivalent 20/200-20/32). This procedure provides meaningful long-term reductions in IOP and the need for IOP-lowering medications without compromising visual rehabilitation in Saudi Arabian eyes with cataract and glaucoma.

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