Institutional Factors Associated with the Incidence Rates of Central Line-associated Bloodstream Infection in California Community Hospitals

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2022 Sep 30

PMID 36178895

Authors

Ella Calixta Nelson

Chia-Hui Wang

Garry Huang

Nai-Wen Kuo

Affiliations

Soon will be listed here.

Abstract

Central line-associated bloodstream infections are frequent, deadly, costly, and preventable. The study aimed to explore how some hospital-related characteristics were associated with incidence rates of central line-associated bloodstream infections reported by community hospitals in California from January to December 2019. This retrospective, cross-sectional study used combined data from records submitted to the California Department of Public Health, California Open Data Portal, the California Health and Human Services Open Data Portal, and the American Hospital Directory by community hospitals in California with central line-associated bloodstream infections in 2019. Results showed that CLABSIs are significantly associated with bed capacity, health care system affiliation, ownership, and hospital accreditation status (p < 0.0001). CLABSI remains a relevant threat to patient safety and quality of care, even more so in the community hospital setting. Understanding if a relationship exists between institutional factors and CLABSI rates might better prepare leaders in healthcare organizations to reduce HAIs.

Citing Articles

National partnerships address critical needs in infection prevention and control.

Kaufman West E, Doll M, Fitzpatrick M, Lewis J, Nori P, Passaretti C Antimicrob Steward Healthc Epidemiol. 2024; 4(1):e213.

PMID: 39654591 PMC: 11626458. DOI: 10.1017/ash.2024.447.

Incorporation of Ceragenins into Medical Adhesives and Adhesive Scar Tape to Prevent Microbial Colonization Common in Healthcare-Associated Infections.

Zaugg A, Sherren E, Yi R, Farnsworth A, Pauga F, Linder A Antibiotics (Basel). 2024; 13(11).

PMID: 39596697 PMC: 11591062. DOI: 10.3390/antibiotics13111002.

Demographic-based disparities in outcomes for adults with central line-associated bloodstream infections in the United States: a National Inpatient Sample database study (2016-2020).

Dix M, Belleville T, Mishra A, Walters R, Millner P, Abdul Jabbar A Front Med (Lausanne). 2024; 11:1469522.

PMID: 39464273 PMC: 11502380. DOI: 10.3389/fmed.2024.1469522.

Monitoring and Outcomes of Central Line-Associated Bloodstream Infections in a Tertiary Care Intensive Care Unit.

Kharduit P, Dutta K, Lyngdoh C, Bhattacharyya P, Lyngdoh V, Khyriem A Cureus. 2024; 16(6):e63428.

PMID: 39077255 PMC: 11284343. DOI: 10.7759/cureus.63428.

References

Britt M . Infectious diseases in small hospitals. Prevalence of infections and adequacy of microbiology services. Ann Intern Med. 1978; 89(5 Pt 2 Suppl):757-60. DOI: 10.7326/0003-4819-89-5-757. View

Rosenthal V, Lynch P, Jarvis W, Khader I, Richtmann R, Jaballah N . Socioeconomic impact on device-associated infections in limited-resource neonatal intensive care units: findings of the INICC. Infection. 2011; 39(5):439-50. DOI: 10.1007/s15010-011-0136-2. View

Lee G, Kleinman K, Soumerai S, Tse A, Cole D, Fridkin S . Effect of nonpayment for preventable infections in U.S. hospitals. N Engl J Med. 2012; 367(15):1428-37. DOI: 10.1056/NEJMsa1202419. View

Raad I, Hanna H, Maki D . Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lancet Infect Dis. 2007; 7(10):645-57. DOI: 10.1016/S1473-3099(07)70235-9. View

Dudeck M, Edwards J, Allen-Bridson K, Gross C, Malpiedi P, Peterson K . National Healthcare Safety Network report, data summary for 2013, Device-associated Module. Am J Infect Control. 2015; 43(3):206-21. PMC: 4653815. DOI: 10.1016/j.ajic.2014.11.014. View

Al-Rawajfah O, Hewitt J, Stetzer F, Cheema J . Length of stay and charges associated with health care-acquired bloodstream infections. Am J Infect Control. 2011; 40(3):227-32. DOI: 10.1016/j.ajic.2011.03.014. View

Zimlichman E, Henderson D, Tamir O, Franz C, Song P, Yamin C . Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med. 2013; 173(22):2039-46. DOI: 10.1001/jamainternmed.2013.9763. View

Hugonnet S, Harbarth S, Sax H, Duncan R, Pittet D . Nursing resources: a major determinant of nosocomial infection?. Curr Opin Infect Dis. 2004; 17(4):329-33. DOI: 10.1097/01.qco.0000136931.83167.d2. View

Barnes H, Rearden J, McHugh M . Magnet® Hospital Recognition Linked to Lower Central Line-Associated Bloodstream Infection Rates. Res Nurs Health. 2016; 39(2):96-104. PMC: 4806525. DOI: 10.1002/nur.21709. View

10.

Rajaram R, Chung J, Kinnier C, Barnard C, Mohanty S, Pavey E . Hospital Characteristics Associated With Penalties in the Centers for Medicare & Medicaid Services Hospital-Acquired Condition Reduction Program. JAMA. 2015; 314(4):375-83. DOI: 10.1001/jama.2015.8609. View

11.

Ricketts 3rd T, Heaphy P . Hospitals in rural America. West J Med. 2000; 173(6):418-22. PMC: 1071201. DOI: 10.1136/ewjm.173.6.418. View

12.

Mermel L . Prevention of intravascular catheter-related infections. Ann Intern Med. 2000; 132(5):391-402. DOI: 10.7326/0003-4819-132-5-200003070-00009. View

13.

Rosenthal V, Guzman S, Migone O, Crnich C . The attributable cost, length of hospital stay, and mortality of central line-associated bloodstream infection in intensive care departments in Argentina: A prospective, matched analysis. Am J Infect Control. 2003; 31(8):475-80. DOI: 10.1016/j.ajic.2003.03.002. View

14.

Sax H, Pittet D . Interhospital differences in nosocomial infection rates: importance of case-mix adjustment. Arch Intern Med. 2002; 162(21):2437-42. DOI: 10.1001/archinte.162.21.2437. View

15.

Sousa P, Uva A, Serranheira F, Sousa Uva M, Nunes C . Patient and hospital characteristics that influence incidence of adverse events in acute public hospitals in Portugal: a retrospective cohort study. Int J Qual Health Care. 2018; 30(2):132-137. PMC: 5890867. DOI: 10.1093/intqhc/mzx190. View

16.

Berenholtz S, Lubomski L, Weeks K, Goeschel C, Marsteller J, Pham J . Eliminating central line-associated bloodstream infections: a national patient safety imperative. Infect Control Hosp Epidemiol. 2013; 35(1):56-62. DOI: 10.1086/674384. View

17.

Warren D, Zack J, Cox M, Cohen M, Fraser V . An educational intervention to prevent catheter-associated bloodstream infections in a nonteaching, community medical center. Crit Care Med. 2003; 31(7):1959-63. DOI: 10.1097/01.CCM.0000069513.15417.1C. View

18.

Burke J . Infection control - a problem for patient safety. N Engl J Med. 2003; 348(7):651-6. DOI: 10.1056/NEJMhpr020557. View

19.

Lorente L, Henry C, Martin M, Jimenez A, Mora M . Central venous catheter-related infection in a prospective and observational study of 2,595 catheters. Crit Care. 2005; 9(6):R631-5. PMC: 1414031. DOI: 10.1186/cc3824. View

20.

Warren D, Zack J, Elward A, Cox M, Fraser V . Nosocomial primary bloodstream infections in intensive care unit patients in a nonteaching community medical center: a 21-month prospective study. Clin Infect Dis. 2001; 33(8):1329-35. DOI: 10.1086/322483. View