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Has Influenza B/Yamagata Become Extinct and What Implications Might This Have for Quadrivalent Influenza Vaccines?

Overview
Journal Euro Surveill
Specialty Infectious Diseases
Date 2022 Sep 30
PMID 36177871
Authors
John Paget
Saverio Caini
Marco Del Riccio
Willemijn van Waarden
Adam Meijer
Affiliations
Soon will be listed here.
Abstract

While two influenza B virus lineages have co-circulated, B/Yamagata-lineage circulation has not been confirmed since March 2020. The WHO FluNet database indicates that B/Yamagata-lineage detections were reported in 2021 and 2022. However, detections can result from use of quadrivalent live-attenuated vaccines. Of the type B viruses detected post-March 2020, all ascribed to a lineage have been B/Victoria-lineage. There is need for a global effort to detect and lineage-ascribe type B influenza viruses, to assess if B/Yamagata-lineage viruses have become extinct.

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