Dual Drug Delivery Platforms for Bone Tissue Engineering

Overview

Journal Front Bioeng Biotechnol

Date 2022 Sep 29

PMID 36172012

Authors

Anupama Devi V K

Sarbajit Ray

Udita Arora

Sunrito Mitra

Alina Sionkowska

Amit Kumar Jaiswal

Affiliations

Soon will be listed here.

Abstract

The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement by altering various parameters of the carrier platform. The platforms thus used are fabricated to mimic the niche of the bone microenvironment, either in the form of porous 3D structures, microspheres, or films. Thus, this review article focuses on the concept of dual drug delivery platform and its importance, classification of various platforms for dual drug delivery specific to bone tissue engineering, and finally highlights the foresight into the future direction of these techniques for better clinical applications.

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