Intranasal Sufentanil Combined with Intranasal Dexmedetomidine: A Promising Method for Non-anesthesiologist Sedation During Endoscopic Ultrasonography

Overview

Journal World J Clin Cases

Publisher Baishideng Publishing Group

Specialty General Medicine

Date 2022 Sep 26

PMID 36159524

Authors

Yong Wang

Zhi-Jun Ge

Chao Han

Affiliations

Soon will be listed here.

Abstract

Intranasal sufentanil combined with intranasal dexmedetomidine exhibited an estimated sedation success probability as high as 94.9%, higher satisfaction scores, and only minor adverse events during endoscopic ultrasonography (EUS). This is a promising method for EUS sedation that does not require the presence of an anesthesiologist.

References

Sidhu R, Turnbull D, Newton M, Thomas-Gibson S, Sanders D, Hebbar S . Deep sedation and anaesthesia in complex gastrointestinal endoscopy: a joint position statement endorsed by the British Society of Gastroenterology (BSG), Joint Advisory Group (JAG) and Royal College of Anaesthetists (RCoA). Frontline Gastroenterol. 2019; 10(2):141-147. PMC: 6540268. DOI: 10.1136/flgastro-2018-101145. View

Guimaraes E, Campbell E, Richter J . The safety of nurse-administered procedural sedation compared to anesthesia care in a historical cohort of advanced endoscopy patients. Anesth Analg. 2014; 119(2):349-356. DOI: 10.1213/ANE.0000000000000258. View

Zou Y, Li N, Shao L, Liu F, Xue F, Tao X . Determination of the ED of intranasal sufentanil combined with intranasal dexmedetomidine for moderate sedation during endoscopic ultrasonography. World J Clin Cases. 2022; 10(9):2773-2782. PMC: 8968820. DOI: 10.12998/wjcc.v10.i9.2773. View

Teh J, Shabbir A, Yuen S, So J . Recent advances in diagnostic upper endoscopy. World J Gastroenterol. 2020; 26(4):433-447. PMC: 7002908. DOI: 10.3748/wjg.v26.i4.433. View

De Lisi S, Giovannini M . Endoscopic ultrasonography: Transition towards the future of gastro-intestinal diseases. World J Gastroenterol. 2016; 22(5):1779-86. PMC: 4724609. DOI: 10.3748/wjg.v22.i5.1779. View

Perel A . Non-anaesthesiologists should not be allowed to administer propofol for procedural sedation: a Consensus Statement of 21 European National Societies of Anaesthesia. Eur J Anaesthesiol. 2011; 28(8):580-4. DOI: 10.1097/EJA.0b013e328348a977. View

Helmers J, Noorduin H, Van Peer A, van Leeuwen L, Zuurmond W . Comparison of intravenous and intranasal sufentanil absorption and sedation. Can J Anaesth. 1989; 36(5):494-7. DOI: 10.1007/BF03005373. View

Gan T, Berry B, Ekman E, Muckerman 2nd R, Shore N, Hardi R . Safety evaluation of fospropofol for sedation during minor surgical procedures. J Clin Anesth. 2010; 22(4):260-7. DOI: 10.1016/j.jclinane.2009.08.007. View

Tanaka H, Matsusaki S . The Utility of Endoscopic-Ultrasonography-Guided Tissue Acquisition for Solid Pancreatic Lesions. Diagnostics (Basel). 2022; 12(3). PMC: 8947755. DOI: 10.3390/diagnostics12030753. View

10.

Pastis N, Hill N, Yarmus L, Schippers F, Imre M, Sohngen W . Correlation of Vital Signs and Depth of Sedation by Modified Observer's Assessment of Alertness and Sedation (MOAA/S) Scale in Bronchoscopy. J Bronchology Interv Pulmonol. 2021; 29(1):54-61. DOI: 10.1097/LBR.0000000000000784. View

11.

Weerink M, Struys M, Hannivoort L, Barends C, Absalom A, Colin P . Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine. Clin Pharmacokinet. 2017; 56(8):893-913. PMC: 5511603. DOI: 10.1007/s40262-017-0507-7. View

12.

Qin Y, Chen S, Zhang Y, Liu W, Lin Y, Chi X . A Bibliometric Analysis of Endoscopic Sedation Research: 2001-2020. Front Med (Lausanne). 2022; 8:775495. PMC: 8761812. DOI: 10.3389/fmed.2021.775495. View

13.

Su Q, Peng J, Chen X, Xiao Z, Liu R, Wang F . Role of endoscopic ultrasonography for differential diagnosis of upper gastrointestinal submucosal lesions. BMC Gastroenterol. 2021; 21(1):365. PMC: 8495965. DOI: 10.1186/s12876-021-01945-9. View

14.

Redondo-Cerezo E, Sanchez-Robaina A, Martinez Cara J, Ojeda-Hinojosa M, Matas-Cobos A, Sanchez Capilla A . Gastroenterologist-guided sedation with propofol for endoscopic ultrasonography in average-risk and high-risk patients: a prospective series. Eur J Gastroenterol Hepatol. 2012; 24(5):506-12. DOI: 10.1097/MEG.0b013e328350fcbd. View

15.

Fatima H, DeWitt J, LeBlanc J, Sherman S, McGreevy K, Imperiale T . Nurse-administered propofol sedation for upper endoscopic ultrasonography. Am J Gastroenterol. 2008; 103(7):1649-56. DOI: 10.1111/j.1572-0241.2008.01906.x. View