» Articles » PMID: 36157380

Plasmacytoid Urothelial Carcinoma of the Bladder That Manifests Disseminated Carcinomatosis of the Bone Marrow: A Case Report of Extremely Rapid Progression

Overview
Journal Case Rep Urol
Publisher Wiley
Specialty Urology
Date 2022 Sep 26
PMID 36157380
Authors
Affiliations
Soon will be listed here.
Abstract

Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare variant of invasive urothelial carcinoma (UC) with aggressive behavior. Despite its prognosis being poorer than that of conventional UC, a median overall survival of approximately 2 years is ensured when it is treated with radical cystectomy (RC), and few patients die within a few months of RC. In this paper, we report the case of a patient with PUC who developed widespread bone metastasis only 6 weeks after RC, which resulted in death within 2 months postoperatively.

Citing Articles

Differentiation Between Disseminated Carcinomatosis of the Bone Marrow From Urothelial Cancer and Intravascular Large B-cell Lymphoma: A Case Report.

Ohta R, Nishikura N, Suyama S, Sano C Cureus. 2024; 16(3):e57221.

PMID: 38686250 PMC: 11056314. DOI: 10.7759/cureus.57221.


An autopsy case of disseminated carcinomatosis of the bone marrow from esophageal adenocarcinoma.

Suzuki D, Meguro S, Furusawa S, Hashimoto N, Kawasaki H, Kosugi I Clin Case Rep. 2023; 11(9):e7877.

PMID: 37744630 PMC: 10511695. DOI: 10.1002/ccr3.7877.

References
1.
Sood S, Paner G . Plasmacytoid Urothelial Carcinoma: An Unusual Variant That Warrants Aggressive Management and Critical Distinction on Transurethral Resections. Arch Pathol Lab Med. 2019; 143(12):1562-1567. DOI: 10.5858/arpa.2018-0139-RS. View

2.
Erdemir F, Ozcan F, Kilicaslan I, Parlaktas B, Uluocak N, Gokce O . The relationship between the expression of E-cadherin and tumor recurrence and progression in high-grade stage T1 bladder urothelial carcinoma. Int Urol Nephrol. 2007; 39(4):1031-7. DOI: 10.1007/s11255-006-9159-5. View

3.
Mir M, Marchioni M, Zargar H, Zargar-Shoshtari K, Fairey A, Mertens L . Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium. Eur Urol Focus. 2020; 7(6):1347-1354. DOI: 10.1016/j.euf.2020.07.002. View

4.
Keck B, Wach S, Kunath F, Bertz S, Taubert H, Lehmann J . Nuclear E-cadherin expression is associated with the loss of membranous E-cadherin, plasmacytoid differentiation and reduced overall survival in urothelial carcinoma of the bladder. Ann Surg Oncol. 2012; 20(7):2440-5. DOI: 10.1245/s10434-012-2709-4. View

5.
Keck B, Wach S, Stoehr R, Kunath F, Bertz S, Lehmann J . Plasmacytoid variant of bladder cancer defines patients with poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy. BMC Cancer. 2013; 13:71. PMC: 3572418. DOI: 10.1186/1471-2407-13-71. View