A Cross-Sectional Comparative Study of Sleep Disturbances in Children with ADHD and Matched Controls

Overview

Journal Brain Sci

Publisher MDPI

Date 2022 Sep 23

PMID 36138894

Authors

Angela Ann Joseph

Anupama Gupta

Nandita Hazari

Mani Kalaivani

Ravindra Mohan Pandey

Rajesh Sagar

Manju Mehta

Garima Shukla

Affiliations

Soon will be listed here.

Abstract

Background: Systematic reviews conducted on sleep disturbances in attention deficit hyperactivity disorder (ADHD) have found inconsistent results due to the presence of several moderating variables which were not controlled for in previous studies. The aim of this study was to examine sleep disturbances in children with ADHD compared to their typically developing peers after controlling for moderating variables (age, sex, medication status, body mass index, and psychiatric and medical comorbidities). Methods: ADHD was diagnosed using DSM-IV-TR criteria (Diagnostic and Statistical Manual of Mental Disorders) and Conners’ Parent Rating Scales. Children recruited (aged 6−12 years) for the ADHD group (n = 40) met the following criteria: IQ > 80, unmedicated, and no psychiatric or medical comorbidities. The control group consisted of age- and sex-matched typically developing peers (n = 40). Sleep was assessed subjectively (through parent reported questionnaires and sleep logs) and objectively (using video polysomnography). Results: 65% of children with ADHD had a sleep disorder, as compared to 17% of controls. The ADHD group reported more sleep disturbances and disorders, both on subjective measures and objective measures. Conclusions: Sleep disturbances and primary sleep disorders in children with ADHD exist independent of moderating variables and differences in sleep assessment methods, thereby bolstering support for previously documented literature on the ADHD and sleep connection.

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References

Silvestri R, Gagliano A, Arico I, Calarese T, Cedro C, Bruni O . Sleep disorders in children with Attention-Deficit/Hyperactivity Disorder (ADHD) recorded overnight by video-polysomnography. Sleep Med. 2009; 10(10):1132-8. DOI: 10.1016/j.sleep.2009.04.003. View

Sierra Montoya A, Mesa Restrepo S, Cuartas Arias J, Cornejo Ochoa W . Prevalence and Clinical Characteristics of the Restless Legs Syndrome (RLS) in Patients Diagnosed with Attention-Deficit Hyperactivity Disorder (ADHD) in Antioquia. Int J Psychol Res (Medellin). 2020; 11(1):58-69. PMC: 7110177. DOI: 10.21500/20112084.3381. View

Frye S, Fernandez-Mendoza J, Calhoun S, Vgontzas A, Liao D, Bixler E . Neurocognitive and behavioral significance of periodic limb movements during sleep in adolescents with attention-deficit/hyperactivity disorder. Sleep. 2018; 41(10). PMC: 6187105. DOI: 10.1093/sleep/zsy129. View

Kapoor V, Ferri R, Stein M, Ruth C, Reed J, DelRosso L . Restless sleep disorder in children with attention-deficit/hyperactivity disorder. J Clin Sleep Med. 2020; 17(4):639-643. PMC: 8020699. DOI: 10.5664/jcsm.8984. View

Marcotte A, Thacher P, Butters M, Bortz J, Acebo C, Carskadon M . Parental report of sleep problems in children with attentional and learning disorders. J Dev Behav Pediatr. 1998; 19(3):178-86. DOI: 10.1097/00004703-199806000-00005. View

Biederman J, Faraone S . Attention-deficit hyperactivity disorder. Lancet. 2005; 366(9481):237-48. DOI: 10.1016/S0140-6736(05)66915-2. View

Konofal E, Cortese S, Marchand M, Mouren M, Arnulf I, Lecendreux M . Impact of restless legs syndrome and iron deficiency on attention-deficit/hyperactivity disorder in children. Sleep Med. 2007; 8(7-8):711-5. DOI: 10.1016/j.sleep.2007.04.022. View

Owens J . The ADHD and sleep conundrum: a review. J Dev Behav Pediatr. 2005; 26(4):312-22. DOI: 10.1097/00004703-200508000-00011. View

Golan N, Shahar E, Ravid S, Pillar G . Sleep disorders and daytime sleepiness in children with attention-deficit/hyperactive disorder. Sleep. 2004; 27(2):261-6. DOI: 10.1093/sleep/27.2.261. View

10.

Tong L, Ye Y, Yan Q . The moderating roles of bedtime activities and anxiety/depression in the relationship between attention-deficit/hyperactivity disorder symptoms and sleep problems in children. BMC Psychiatry. 2018; 18(1):298. PMC: 6148953. DOI: 10.1186/s12888-018-1879-4. View

11.

Sadeh A, Pergamin L, Bar-Haim Y . Sleep in children with attention-deficit hyperactivity disorder: a meta-analysis of polysomnographic studies. Sleep Med Rev. 2006; 10(6):381-98. DOI: 10.1016/j.smrv.2006.03.004. View

12.

Lal C, Strange C, Bachman D . Neurocognitive impairment in obstructive sleep apnea. Chest. 2012; 141(6):1601-1610. DOI: 10.1378/chest.11-2214. View

13.

Yoon S, Jain U, Shapiro C . Sleep in attention-deficit/hyperactivity disorder in children and adults: past, present, and future. Sleep Med Rev. 2011; 16(4):371-88. DOI: 10.1016/j.smrv.2011.07.001. View

14.

Sanabra M, Gomez-Hinojosa T, Grau N, Alda J . Deficient Emotional Self-Regulation and Sleep Problems in ADHD with and without Pharmacological Treatment. J Atten Disord. 2021; 26(3):426-433. DOI: 10.1177/1087054720986242. View

15.

Cavalli E, Anders R, Chaussoy L, Herbillon V, Franco P, Putois B . Screen exposure exacerbates ADHD symptoms indirectly through increased sleep disturbance. Sleep Med. 2021; 83:241-247. DOI: 10.1016/j.sleep.2021.03.010. View

16.

Castano-De la Mota C, Moreno-Acero N, Pozo R, Soto-Insuga V, Perez-Villena A, Rodriguez-Fernandez C . [Restless legs syndrome in patients diagnosed with attention deficit hyperactivity disorder]. Rev Neurol. 2017; 64(7):299-304. View

17.

Bondopadhyay U, Diaz-Orueta U, Coogan A . A Systematic Review of Sleep and Circadian Rhythms in Children with Attention Deficit Hyperactivity Disorder. J Atten Disord. 2021; 26(2):149-224. DOI: 10.1177/1087054720978556. View

18.

Cortese S, Lecendreux M, Mouren M, Konofal E . ADHD and insomnia. J Am Acad Child Adolesc Psychiatry. 2006; 45(4):384-5. DOI: 10.1097/01.chi.0000199577.12145.bc. View

19.

Crabtree V, Ivanenko A, Gozal D . Clinical and parental assessment of sleep in children with attention-deficit/hyperactivity disorder referred to a pediatric sleep medicine center. Clin Pediatr (Phila). 2003; 42(9):807-13. DOI: 10.1177/000992280304200906. View

20.

Willcutt E . The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. Neurotherapeutics. 2012; 9(3):490-9. PMC: 3441936. DOI: 10.1007/s13311-012-0135-8. View