Dual-Energy CT of the Heart: A Review

Overview

Journal J Imaging

Publisher MDPI

Specialty Radiology

Date 2022 Sep 22

PMID 36135402

Authors

Serena DellAversana

Raffaele Ascione

Marco De Giorgi

Davide Raffaele De Lucia

Renato Cuocolo

Marco Boccalatte

Gerolamo Sibilio

Giovanni Napolitano

Giuseppe Muscogiuri

Sandro Sironi

Giuseppe Di Costanzo

Enrico Cavaglia

Massimo Imbriaco

Andrea Ponsiglione

Affiliations

Soon will be listed here.

Abstract

Dual-energy computed tomography (DECT) represents an emerging imaging technique which consists of the acquisition of two separate datasets utilizing two different X-ray spectra energies. Several cardiac DECT applications have been assessed, such as virtual monoenergetic images, virtual non-contrast reconstructions, and iodine myocardial perfusion maps, which are demonstrated to improve diagnostic accuracy and image quality while reducing both radiation and contrast media administration. This review will summarize the technical basis of DECT and review the principal cardiac applications currently adopted in clinical practice, exploring possible future applications.

Citing Articles

State of the art of CT myocardial perfusion.

Muscogiuri G, Palumbo P, Kitagawa K, Nakamura S, Senatieri A, De Cecco C Radiol Med. 2024; 130(3):438-452.

PMID: 39704963 DOI: 10.1007/s11547-024-01942-4.

Head and Neck Squamous Cell Carcinoma: Insights from Dual-Energy Computed Tomography (DECT).

Bicci E, Di Finizio A, Calamandrei L, Treballi F, Mungai F, Tamburrini S Tomography. 2024; 10(11):1780-1797.

PMID: 39590940 PMC: 11598236. DOI: 10.3390/tomography10110131.

Cardiovascular Aging and Risk Assessment: How Multimodality Imaging Can Help.

Hrabak Paar M, Mursic M, Bremerich J, Heye T Diagnostics (Basel). 2024; 14(17).

PMID: 39272731 PMC: 11393882. DOI: 10.3390/diagnostics14171947.

Trends and hotspots of energy-based imaging in thoracic disease: a bibliometric analysis.

Chen Y, Wu T, Zhu Y, Chen J, Gao C, Wu L Insights Imaging. 2024; 15(1):209.

PMID: 39143273 PMC: 11324624. DOI: 10.1186/s13244-024-01788-4.

What to Expect (and What Not) from Dual-Energy CT Imaging Now and in the Future?.

Garcia-Figueiras R, Oleaga L, Broncano J, Tardaguila G, Fernandez-Perez G, Vano E J Imaging. 2024; 10(7).

PMID: 39057725 PMC: 11278514. DOI: 10.3390/jimaging10070154.

References

Martin S, Wichmann J, Weyer H, Scholtz J, Leithner D, Spandorfer A . Endoleaks after endovascular aortic aneurysm repair: Improved detection with noise-optimized virtual monoenergetic dual-energy CT. Eur J Radiol. 2017; 94:125-132. DOI: 10.1016/j.ejrad.2017.06.017. View

Deseive S, Bauer R, Lehmann R, Kettner M, Kaiser C, Korkusuz H . Dual-energy computed tomography for the detection of late enhancement in reperfused chronic infarction: a comparison to magnetic resonance imaging and histopathology in a porcine model. Invest Radiol. 2011; 46(7):450-6. DOI: 10.1097/RLI.0b013e3182145b4f. View

Wang R, Yu W, Wang Y, He Y, Yang L, Bi T . Incremental value of dual-energy CT to coronary CT angiography for the detection of significant coronary stenosis: comparison with quantitative coronary angiography and single photon emission computed tomography. Int J Cardiovasc Imaging. 2011; 27(5):647-56. DOI: 10.1007/s10554-011-9881-7. View

Mahnken A, Lautenschlager S, Fritz D, Koos R, Scheuering M . Perfusion weighted color maps for enhanced visualization of myocardial infarction by MSCT: preliminary experience. Int J Cardiovasc Imaging. 2008; 24(8):883-90. DOI: 10.1007/s10554-008-9318-0. View

Si-Mohamed S, Restier L, Branchu A, Boccalini S, Congi A, Ziegler A . Diagnostic Performance of Extracellular Volume Quantified by Dual-Layer Dual-Energy CT for Detection of Acute Myocarditis. J Clin Med. 2021; 10(15). PMC: 8348100. DOI: 10.3390/jcm10153286. View

Song I, Yi J, Park J, Kim S, Lee K, Chung M . Virtual Non-Contrast CT Using Dual-Energy Spectral CT: Feasibility of Coronary Artery Calcium Scoring. Korean J Radiol. 2016; 17(3):321-9. PMC: 4842852. DOI: 10.3348/kjr.2016.17.3.321. View

Sandfort V, Persson M, Pourmorteza A, Noel P, Fleischmann D, Willemink M . Spectral photon-counting CT in cardiovascular imaging. J Cardiovasc Comput Tomogr. 2020; 15(3):218-225. DOI: 10.1016/j.jcct.2020.12.005. View

Albrecht M, Bickford M, Nance Jr J, Zhang L, De Cecco C, Wichmann J . State-of-the-Art Pulmonary CT Angiography for Acute Pulmonary Embolism. AJR Am J Roentgenol. 2016; 208(3):495-504. DOI: 10.2214/AJR.16.17202. View

Qi R, Shao J, Jiang J, Ruan X, Huang S, Zhang Q . Myocardial extracellular volume fraction quantitation using cardiac dual-energy CT with late iodine enhancement in patients with heart failure without coronary artery disease: A single-center prospective study. Eur J Radiol. 2021; 140:109743. DOI: 10.1016/j.ejrad.2021.109743. View

10.

Oda S, Takaoka H, Katahira K, Honda K, Nakaura T, Nagayama Y . Low contrast material dose coronary computed tomographic angiography using a dual-layer spectral detector system in patients at risk for contrast-induced nephropathy. Br J Radiol. 2018; 92(1094):20180215. PMC: 6404842. DOI: 10.1259/bjr.20180215. View

11.

Bauer R, Kerl J, Fischer N, Burkhard T, Larson M, Ackermann H . Dual-energy CT for the assessment of chronic myocardial infarction in patients with chronic coronary artery disease: comparison with 3-T MRI. AJR Am J Roentgenol. 2010; 195(3):639-46. DOI: 10.2214/AJR.09.3849. View

12.

De Cecco C, Schoepf U, Steinbach L, Boll D, Foley W, Kaza R . White Paper of the Society of Computed Body Tomography and Magnetic Resonance on Dual-Energy CT, Part 3: Vascular, Cardiac, Pulmonary, and Musculoskeletal Applications. J Comput Assist Tomogr. 2017; 41(1):1-7. DOI: 10.1097/RCT.0000000000000538. View

13.

Meyer M, Haubenreisser H, Schoepf U, Vliegenthart R, Leidecker C, Allmendinger T . Closing in on the K edge: coronary CT angiography at 100, 80, and 70 kV-initial comparison of a second- versus a third-generation dual-source CT system. Radiology. 2014; 273(2):373-82. DOI: 10.1148/radiol.14140244. View

14.

Cavallo A, Patterson A, Thomas R, Alaiti M, Attizzani G, Laukamp K . Low dose contrast CT for transcatheter aortic valve replacement assessment: Results from the prospective SPECTACULAR study (spectral CT assessment prior to TAVR). J Cardiovasc Comput Tomogr. 2019; 14(1):68-74. DOI: 10.1016/j.jcct.2019.06.015. View

15.

Bamberg F, Dierks A, Nikolaou K, Reiser M, Becker C, Johnson T . Metal artifact reduction by dual energy computed tomography using monoenergetic extrapolation. Eur Radiol. 2011; 21(7):1424-9. DOI: 10.1007/s00330-011-2062-1. View

16.

De Cecco C, Darnell A, Rengo M, Muscogiuri G, Bellini D, Ayuso C . Dual-energy CT: oncologic applications. AJR Am J Roentgenol. 2012; 199(5 Suppl):S98-S105. DOI: 10.2214/AJR.12.9207. View

17.

De Santis D, Eid M, De Cecco C, Jacobs B, Albrecht M, Varga-Szemes A . Dual-Energy Computed Tomography in Cardiothoracic Vascular Imaging. Radiol Clin North Am. 2018; 56(4):521-534. DOI: 10.1016/j.rcl.2018.03.010. View

18.

DAngelo T, Bucher A, Lenga L, Arendt C, Peterke J, Caruso D . Optimisation of window settings for traditional and noise-optimised virtual monoenergetic imaging in dual-energy computed tomography pulmonary angiography. Eur Radiol. 2017; 28(4):1393-1401. DOI: 10.1007/s00330-017-5059-6. View

19.

So A, Hsieh J, Narayanan S, Thibault J, Imai Y, Dutta S . Dual-energy CT and its potential use for quantitative myocardial CT perfusion. J Cardiovasc Comput Tomogr. 2012; 6(5):308-17. DOI: 10.1016/j.jcct.2012.07.002. View

20.

Hell M, Bittner D, Schuhbaeck A, Muschiol G, Brand M, Lell M . Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effect of iterative reconstruction. J Cardiovasc Comput Tomogr. 2014; 8(6):418-25. DOI: 10.1016/j.jcct.2014.09.003. View