The Role of Aging in Cancer
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Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects including somatic mutations, proteostasis, mitochondria, metabolism, senescence, epigenetic regulation, immune regulation, DNA damage, and telomere function.
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PMID: 39981889 PMC: 11844339. DOI: 10.3892/ijo.2025.5729.
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PMID: 39940287 PMC: 11820085. DOI: 10.3390/nu17030429.
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PMID: 39906716 PMC: 11788355. DOI: 10.3389/fnagi.2025.1533963.
Telomere length and polymorphisms as biomarkers in asbestos-related diseases.
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PMID: 38378028 PMC: 10878767. DOI: 10.2478/raon-2024-0009.
HOMA-IR is positively correlated with biological age and advanced aging in the US adult population.
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PMID: 37898776 PMC: 10612177. DOI: 10.1186/s40001-023-01448-1.