» Articles » PMID: 36122487

How Has the COVID-19 Pandemic Impacted Clinical Care and Research in Neuro-Oncology?

Overview
Journal J Clin Neurosci
Specialty Neurology
Date 2022 Sep 19
PMID 36122487
Authors
Affiliations
Soon will be listed here.
Abstract

The COVID-19 pandemic has challenged the continued delivery of healthcare globally. Due to disease risk, clinicians were forced to re-evaluate the safety and priorities of pre-pandemic care. Neuro-oncology presents unique challenges, as patients can deteriorate rapidly without intervention. These challenges were also observed in countries with reduced COVID-19 burden with centres required to rapidly develop strategies to maintain efficient and equitable care. This review aims to summarise the impact of the pandemic on clinical care and research within the practice of Neuro-oncology. A narrative review of the literature was performed using MEDLINE and EMBASS and results screened using PRISMA guidelines with relevant inclusion and exclusion criteria. Search strategies included variations of 'Neuro-oncology' combined with COVID-19 and other clinical-related terms. Most adult and paediatric neurosurgical centres experienced reductions in new referrals and operations for brain malignancies, and those who did present for treatment frequently had operations cancelled or delayed. Many radiation therapy and medical oncology centres altered treatment plans to mitigate COVID-19 risk for patients and staff. New protocols were developed that aimed to reduce in-person visits and reduce the risk of developing severe complications from COVID-19. The COVID-19 pandemic has presented many challenges to the provision of safe and accessible healthcare. Despite these challenges, some benefits to healthcare provision such as the use of telemedicine are likely to remain in future practice. Neuro-oncology staff must remain vigilant to ensure patient and staff safety.

Citing Articles

Impact of the SARS-CoV-2/COVID-19 pandemic on the patient journeys of those with a newly diagnosed paediatric brain tumour in the UK: a qualitative study.

Akhter K, Casson R, Brewster L, Burke G, Kilday J, Macarthur D BMJ Open. 2025; 15(1):e086118.

PMID: 39753258 PMC: 11749440. DOI: 10.1136/bmjopen-2024-086118.


Neurosurgical care for patients with high-grade gliomas during the coronavirus disease 2019 pandemic: Analysis of routine billing data of a German nationwide hospital network.

Gerlach R, Dengler J, Bollmann A, Stoffel M, Youssef F, Carl B Neurooncol Pract. 2023; 10(5):429-436.

PMID: 37720392 PMC: 10502769. DOI: 10.1093/nop/npad015.


Non-COVID-19 UK clinical trials and the COVID-19 pandemic: impact, challenges and possible solutions.

Lorenc A, Rooshenas L, Conefrey C, Wade J, Farrar N, Mills N Trials. 2023; 24(1):424.

PMID: 37349850 PMC: 10286467. DOI: 10.1186/s13063-023-07414-w.

References
1.
Iorio-Morin C, Hodaie M, Sarica C, Dea N, Westwick H, Christie S . Letter: The Risk of COVID-19 Infection During Neurosurgical Procedures: A Review of Severe Acute Respiratory Distress Syndrome Coronavirus 2 (SARS-CoV-2) Modes of Transmission and Proposed Neurosurgery-Specific Measures for Mitigation. Neurosurgery. 2020; 87(2):E178-E185. PMC: 7188127. DOI: 10.1093/neuros/nyaa157. View

2.
Fisher A, Patronick J, Gerhardt C, Radonovich K, Salloum R, Wade S . Impact of COVID-19 on adolescent and emerging adult brain tumor survivors and their parents. Pediatr Blood Cancer. 2021; 68(9):e29116. PMC: 8209896. DOI: 10.1002/pbc.29116. View

3.
Lubansu A, El Hadwe S . In Reply to the Letter to the Editor Regarding "COVID-19 Impact on Neurosurgical Practice: Lockdown Attitude and Experience of a European Academic Center". World Neurosurg. 2020; 148:224. PMC: 7605793. DOI: 10.1016/j.wneu.2020.10.143. View

4.
Ahuja S, Shah P, Mohammed R . Impact of COVID-19 pandemic on acute spine surgery referrals to UK tertiary spinal unit: any lessons to be learnt?. Br J Neurosurg. 2021; 35(2):181-185. DOI: 10.1080/02688697.2020.1777263. View

5.
Bernhardt D, Wick W, Weiss S, Sahgal A, Lo S, Suh J . Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas. Neuro Oncol. 2020; . PMC: 7239150. DOI: 10.1093/neuonc/noaa113. View