Chrysin Targets Myeloid-derived Suppressor Cells and Enhances Tumour Response to Anti-PD-1 Immunotherapy

Overview

Journal Clin Transl Med

Publisher Wiley

Specialty General Medicine

Date 2022 Sep 19

PMID 36121176

Authors

Yinan Li

Ru Yang

Xiu Huang

Caihong Chen

Daolei Dou

Qianqian Wang

Xinying Wu

Huijuan Liu

Tao Sun

Affiliations

Soon will be listed here.

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References

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Li K, Shi H, Zhang B, Ou X, Ma Q, Chen Y . Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer. Signal Transduct Target Ther. 2021; 6(1):362. PMC: 8497485. DOI: 10.1038/s41392-021-00670-9. View

Zhou L, Yang C, Zhong W, Wang Q, Zhang D, Zhang J . Chrysin induces autophagy-dependent ferroptosis to increase chemosensitivity to gemcitabine by targeting CBR1 in pancreatic cancer cells. Biochem Pharmacol. 2021; 193:114813. DOI: 10.1016/j.bcp.2021.114813. View

Weber R, Fleming V, Hu X, Nagibin V, Groth C, Altevogt P . Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors. Front Immunol. 2018; 9:1310. PMC: 6004385. DOI: 10.3389/fimmu.2018.01310. View