Biomarkers in Oral Immunotherapy

Overview

Journal J Zhejiang Univ Sci B

Specialties Biology
General Medicine

Date 2022 Sep 16

PMID 36111569

Authors

Haitao Zhu

Kaifa Tang

Guoqiang Chen

Zhongwei Liu

Affiliations

Soon will be listed here.

Abstract

Food allergy (FA) is a global health problem that affects a large population, and thus effective treatment is highly desirable. Oral immunotherapy (OIT) has been showing reasonable efficacy and favorable safety in most FA subjects. Dependable biomarkers are needed for treatment assessment and outcome prediction during OIT. Several immunological indicators have been used as biomarkers in OIT, such as skin prick tests, basophil and mast cell reactivity, T cell and B cell responses, allergen-specific antibody levels, and cytokines. Other novel indicators also could be potential biomarkers. In this review, we discuss and assess the application of various immunological indicators as biomarkers for OIT.

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