Assessment of Knowledge, Awareness, and Perception of Platelet-Rich Plasma Among Oral Surgeons

Overview

Journal J Pharm Bioallied Sci

Specialty Pharmacology

Date 2022 Sep 16

PMID 36110738

Authors

Sujithraj Stephen

Selvakumar Ramar

Chinnaiah Rajendran

Nirmala Mrugesh Devar

I Bevin Shaga

Revathi Somasundaram

Bhuvaneswari Mani

Nagappan Nagappan

S M M Moulvi

Affiliations

Soon will be listed here.

Abstract

Aim: The current survey was conducted to assess the knowledge and awareness of platelet-rich plasma (PRP) among oral surgeons in the state of Tamil Nadu.

Methodology: The cross-sectional questionnaire survey was conducted among oral surgeons in the state of Tamil Nadu. The self-administered questions related to knowledge and awareness of PRP were collected from 500 participants. The statistical analysis was done using Statistical Package for the Social Sciences SPSS (V 22.0). The frequency distribution was computed.

Results: This survey exposed that 454 (90.4%) respondents had knowledge and awareness about the role of PRP. Forty (7.0%) were knowledgeable regarding the PRP treatment. Four hundred and fifty-four (90.6%) had aware about the usage of PRP procedures in oral surgery.

Conclusion: The current study's findings indicate that the oral surgeons were aware of PRP as an auxiliary therapeutic technique for wound healing and maturation.

References

Lee C, David T, Nishime M . Use of platelet-rich plasma in the management of oral biphosphonate-associated osteonecrosis of the jaw: a report of 2 cases. J Oral Implantol. 2008; 33(6):371-82. DOI: 10.1563/1548-1336(2007)33[371:UOPPIT]2.0.CO;2. View

Cetiner S, Sucak G, Kahraman S, Aki S, Kocakahyaoglu B, Elif Gultekin S . Osteonecrosis of the jaw in patients with multiple myeloma treated with zoledronic acid. J Bone Miner Metab. 2009; 27(4):435-43. DOI: 10.1007/s00774-009-0047-9. View

Carlson N, Roach Jr R . Platelet-rich plasma: clinical applications in dentistry. J Am Dent Assoc. 2002; 133(10):1383-6. DOI: 10.14219/jada.archive.2002.0054. View

Marx R, Carlson E, Eichstaedt R, Schimmele S, Strauss J, Georgeff K . Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998; 85(6):638-46. DOI: 10.1016/s1079-2104(98)90029-4. View

Cochran D, Wozney J . Biological mediators for periodontal regeneration. Periodontol 2000. 1999; 19:40-58. DOI: 10.1111/j.1600-0757.1999.tb00146.x. View

Mozzati M, Gallesio G, Arata V, Pol R, Scoletta M . Platelet-rich therapies in the treatment of intravenous bisphosphonate-related osteonecrosis of the jaw: a report of 32 cases. Oral Oncol. 2012; 48(5):469-74. DOI: 10.1016/j.oraloncology.2011.12.004. View

Plachokova A, Nikolidakis D, Mulder J, Jansen J, Creugers N . Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review. Clin Oral Implants Res. 2008; 19(6):539-45. DOI: 10.1111/j.1600-0501.2008.01525.x. View

Adornato M, Morcos I, Rozanski J . The treatment of bisphosphonate-associated osteonecrosis of the jaws with bone resection and autologous platelet-derived growth factors. J Am Dent Assoc. 2007; 138(7):971-7. DOI: 10.14219/jada.archive.2007.0294. View

Fennis J, Stoelinga P, Jansen J . Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats. Int J Oral Maxillofac Surg. 2003; 33(1):48-55. DOI: 10.1054/ijom.2003.0452. View

10.

McCreary C, Riordain R . Systemic diseases and the elderly. Dent Update. 2010; 37(9):604-7. DOI: 10.12968/denu.2010.37.9.604. View

11.

Kao R, Murakami S, Beirne O . The use of biologic mediators and tissue engineering in dentistry. Periodontol 2000. 2009; 50:127-53. DOI: 10.1111/j.1600-0757.2008.00287.x. View

12.

Bocanegra-Perez S, Vicente-Barrero M, Knezevic M, Castellano-Navarro J, Rodriguez-Bocanegra E, Rodriguez-Millares J . Use of platelet-rich plasma in the treatment of bisphosphonate-related osteonecrosis of the jaw. Int J Oral Maxillofac Surg. 2012; 41(11):1410-5. DOI: 10.1016/j.ijom.2012.04.020. View

13.

Anitua E, Andia I, Ardanza B, Nurden P, Nurden A . Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost. 2003; 91(1):4-15. DOI: 10.1160/TH03-07-0440. View

14.

El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M . Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol. 2007; 78(4):661-9. DOI: 10.1902/jop.2007.060302. View

15.

Arora N, Ramanayake T, Ren Y, Romanos G . Platelet-rich plasma in sinus augmentation procedures: a systematic literature review: Part II. Implant Dent. 2010; 19(2):145-57. DOI: 10.1097/ID.0b013e3181cd706d. View

16.

Curi M, Cossolin G, Koga D, Araujo S, Feher O, Dos Santos M . Treatment of avascular osteonecrosis of the mandible in cancer patients with a history of bisphosphonate therapy by combining bone resection and autologous platelet-rich plasma: Report of 3 cases. J Oral Maxillofac Surg. 2007; 65(2):349-55. DOI: 10.1016/j.joms.2005.12.051. View

17.

Bae J, Kim Y, Myung S . Effects of platelet-rich plasma on sinus bone graft: meta-analysis. J Periodontol. 2010; 82(5):660-7. DOI: 10.1902/jop.2010.100529. View

18.

Nikolidakis D, Jansen J . The biology of platelet-rich plasma and its application in oral surgery: literature review. Tissue Eng Part B Rev. 2008; 14(3):249-58. DOI: 10.1089/ten.teb.2008.0062. View

19.

Huttner E, Machado D, Oliveira R, Antunes A, Hebling E . Effects of human aging on periodontal tissues. Spec Care Dentist. 2009; 29(4):149-55. DOI: 10.1111/j.1754-4505.2009.00082.x. View

20.

Del Corso M, Vervelle A, Simonpieri A, Jimbo R, Inchingolo F, Sammartino G . Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 1: Periodontal and dentoalveolar surgery. Curr Pharm Biotechnol. 2011; 13(7):1207-30. DOI: 10.2174/138920112800624391. View