[Time-restricted Eating As a Novel Strategy for Treatment of Obesity and It's Comorbid Conditions]

Overview

Journal Probl Endokrinol (Mosk)

Specialty Endocrinology

Date 2022 Sep 15

PMID 36104969

Authors

M A Berkovskaya

O Y Gurova

I A Khaykina

V V Fadeev

Affiliations

Soon will be listed here.

Abstract

The article provides a review of the current literature about time-restricted eating (TRE) as a new tool for the treatment of obesity and comorbid conditions. The search for new nutritional strategies in obesity, one of which is TRE, is due to the weak adherence of patients to hypocaloric diets in the long term, as well as the available data on the importance of -desynchronization of food intake with natural circadian rhythms in the development and progression of obesity and cardio--metabolic complications. The article describes the main mechanisms that regulate the circadian rhythms of food intake and nutrient absorption, substantiates the importance of adhering to a physiological diet for maintaining metabolic health. The main part of the review is devoted to reviewing the currently available researches on the effectiveness of various strategies of intermittent energy restriction for weight loss and the correction of metabolic parameters. Potential mechanisms of the -effect of TRE on health are discussed, including those mediated by an unintentional decrease in caloric intake and changes in eating behavior, and differences in the effectiveness of early and late TRE. The article contains a detailed discussion of the potential problems and contradictions associated with the use of time-restricted eating in clinical practice, namely: the limitations and inconsistencies of the available clinical trials, the lack of data on long-term efficacy and safety, social and psychological limitations that impede the widespread use of TRE.

References

Shimizu H, Hanzawa F, Kim D, Sun S, Laurent T, Umeki M . Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and shifted the circadian oscillation of the hepatic clock and lipid metabolism-related genes in rats fed a high-fat diet. PLoS One. 2018; 13(10):e0206669. PMC: 6209334. DOI: 10.1371/journal.pone.0206669. View

Allaf M, Elghazaly H, Mohamed O, Fareen M, Zaman S, Salmasi A . Intermittent fasting for the prevention of cardiovascular disease. Cochrane Database Syst Rev. 2021; 1:CD013496. PMC: 8092432. DOI: 10.1002/14651858.CD013496.pub2. View

Martens C, Rossman M, Mazzo M, Jankowski L, Nagy E, Denman B . Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults. Geroscience. 2020; 42(2):667-686. PMC: 7206473. DOI: 10.1007/s11357-020-00156-6. View

Reutrakul S, Hood M, Crowley S, Morgan M, Teodori M, Knutson K . The relationship between breakfast skipping, chronotype, and glycemic control in type 2 diabetes. Chronobiol Int. 2013; 31(1):64-71. DOI: 10.3109/07420528.2013.821614. View

Dsouza A, Neumann U, Glavas M, Kieffer T . The glucoregulatory actions of leptin. Mol Metab. 2017; 6(9):1052-1065. PMC: 5605734. DOI: 10.1016/j.molmet.2017.04.011. View

Singh R, Cornelissen G, Mojto V, Fatima G, Wichansawakun S, Singh M . Effects of circadian restricted feeding on parameters of metabolic syndrome among healthy subjects. Chronobiol Int. 2019; 37(3):395-402. DOI: 10.1080/07420528.2019.1701817. View

Carlson O, Martin B, Stote K, Golden E, Maudsley S, Najjar S . Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women. Metabolism. 2007; 56(12):1729-34. PMC: 2121099. DOI: 10.1016/j.metabol.2007.07.018. View

Boivin D, Boudreau P . Impacts of shift work on sleep and circadian rhythms. Pathol Biol (Paris). 2014; 62(5):292-301. DOI: 10.1016/j.patbio.2014.08.001. View

Yanai H, Yoshida H . Beneficial Effects of Adiponectin on Glucose and Lipid Metabolism and Atherosclerotic Progression: Mechanisms and Perspectives. Int J Mol Sci. 2019; 20(5). PMC: 6429491. DOI: 10.3390/ijms20051190. View

10.

Moro T, Tinsley G, Bianco A, Marcolin G, Pacelli Q, Battaglia G . Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. J Transl Med. 2016; 14(1):290. PMC: 5064803. DOI: 10.1186/s12967-016-1044-0. View

11.

Lopez-Minguez J, Gomez-Abellan P, Garaulet M . Circadian rhythms, food timing and obesity. Proc Nutr Soc. 2016; 75(4):501-511. DOI: 10.1017/S0029665116000628. View

12.

Gasmi M, Sellami M, Denham J, Padulo J, Kuvacic G, Selmi W . Time-restricted feeding influences immune responses without compromising muscle performance in older men. Nutrition. 2018; 51-52:29-37. DOI: 10.1016/j.nut.2017.12.014. View

13.

Manoogian E, Panda S . Circadian rhythms, time-restricted feeding, and healthy aging. Ageing Res Rev. 2016; 39:59-67. PMC: 5814245. DOI: 10.1016/j.arr.2016.12.006. View

14.

Parr E, Devlin B, Lim K, Moresi L, Geils C, Brennan L . Time-Restricted Eating as a Nutrition Strategy for Individuals with Type 2 Diabetes: A Feasibility Study. Nutrients. 2020; 12(11). PMC: 7690416. DOI: 10.3390/nu12113228. View

15.

Hatori M, Vollmers C, Zarrinpar A, DiTacchio L, Bushong E, Gill S . Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab. 2012; 15(6):848-60. PMC: 3491655. DOI: 10.1016/j.cmet.2012.04.019. View

16.

Nakajima K, Suwa K . Association of hyperglycemia in a general Japanese population with late-night-dinner eating alone, but not breakfast skipping alone. J Diabetes Metab Disord. 2015; 14:16. PMC: 4396539. DOI: 10.1186/s40200-015-0147-0. View

17.

St-Onge M, Ard J, Baskin M, Chiuve S, Johnson H, Kris-Etherton P . Meal Timing and Frequency: Implications for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association. Circulation. 2017; 135(9):e96-e121. PMC: 8532518. DOI: 10.1161/CIR.0000000000000476. View

18.

Lowe D, Wu N, Rohdin-Bibby L, Moore A, Kelly N, Liu Y . Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial. JAMA Intern Med. 2020; 180(11):1491-1499. PMC: 7522780. DOI: 10.1001/jamainternmed.2020.4153. View

19.

Yoshida J, Eguchi E, Nagaoka K, Ito T, Ogino K . Association of night eating habits with metabolic syndrome and its components: a longitudinal study. BMC Public Health. 2018; 18(1):1366. PMC: 6288903. DOI: 10.1186/s12889-018-6262-3. View

20.

Rynders C, Thomas E, Zaman A, Pan Z, Catenacci V, Melanson E . Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss. Nutrients. 2019; 11(10). PMC: 6836017. DOI: 10.3390/nu11102442. View